Tchoukoua Abdou, Ota Takuma, Akanuma Rima, Ju Yu-Ming, Supratman Unang, Murayama Tetsuya, Koseki Takuya, Shiono Yoshihito
a Department of Organic Chemistry , University of Yaounde 1 , Yaounde , Cameroon.
b Department of Food, Life, and Environmental Science, Faculty of Agriculture , Yamagata University , Tsuruoka , Japan.
Nat Prod Res. 2017 Sep;31(18):2113-2118. doi: 10.1080/14786419.2016.1277352. Epub 2017 Jan 9.
A new compound, (3aS,6aR)-4,5-dimethyl-3,3a,6,6a-tetrahydro-2H-cyclopenta [b]furan-2-one (2), along with two known metabolites, myrotheciumone A (1) and 4-oxo-4H-pyron-3-acetic acid (3) was isolated from the ethyl acetate extract of fermentation broth of Xylaria curta 92092022. The structures of these compounds were elucidated on the basis of spectroscopic methods (UV, IR, HRESITOFMS, 1D NMR, and 2D NMR). Compounds 1 and 2 showed moderate antibacterial and phytotoxic activities.
从皱瘤褐孔菌92092022发酵液的乙酸乙酯提取物中分离出一种新化合物(3aS,6aR)-4,5-二甲基-3,3a,6,6a-四氢-2H-环戊并[b]呋喃-2-酮(2)，以及两种已知代谢产物，肉色壳菌素A(1)和4-氧代-4H-吡喃-3-乙酸(3)。这些化合物的结构通过光谱方法(紫外、红外、高分辨电喷雾电离飞行时间质谱、一维核磁共振和二维核磁共振)得以阐明。化合物1和2表现出中等的抗菌和植物毒性活性。
