Aix Marseille Univ., IRD, MEPHI, IHU Méditerranée Infection, Marseille, France.
Aix Marseille Univ., INSERM, IRD, SESSTIM, Sciences Economiques & Sociales de la Santé & Traitement de l'Information Médicale, Marseille, France.
Future Microbiol. 2018 Nov;13:1611-1624. doi: 10.2217/fmb-2018-0181. Epub 2018 Nov 12.
While the gut microbiota is currently in the spotlight, the airway microbiome has been recently associated with several pulmonary diseases and carcinogenesis. As there are several biases associated with high-throughput sequencing methods, cultivation techniques are crucial for the investigation of the human microbiome. We thus aimed to build an exhaustive database, including a list of microbes isolated by culture from respiratory specimens, by performing a review of the literature. Herein, we have listed a total of 756 species cultured from the human respiratory tract. This represents 27.23% of the overall bacterial richness captured from human being by culture methods. This repertoire could be valuable for the elucidation of the interactions between the respiratory microbiome and human health.
虽然肠道微生物群目前备受关注,但气道微生物组最近与多种肺部疾病和癌变有关。由于高通量测序方法存在多种偏差,培养技术对于人类微生物组的研究至关重要。因此,我们旨在通过文献综述建立一个详尽的数据库,其中包括通过培养从呼吸道标本中分离出的微生物列表。在此,我们总共列出了 756 种从人类呼吸道培养的物种。这代表了通过培养方法从人类中捕获的总细菌丰富度的 27.23%。该曲目对于阐明呼吸微生物组与人类健康之间的相互作用可能很有价值。