Pushpa S, Maheshwari Chakit, Maheshwari Garima, Sridevi N, Duggal Puneeta, Ahuja Puneet
Department of Conservative Dentistry and Endodontics, Rama Dental College-Hospital and Research Centre, Kanpur - 208024, Uttar Pradesh, India.
J Dent Res Dent Clin Dent Prospects. 2018 Summer;12(3):201-207. doi: 10.15171/joddd.2018.031. Epub 2018 Sep 18.
The aim of this study was to evaluate the effect of acidic, neutral and alkaline environments on the solubility of white mineral trioxide aggregate (WMTA) and Biodentine (BD). Thirty-nine ring molds were randomly divided into three groups of A, B, and C (n = 12) with pH values of 7.4, 4.4 and 10.4, respectively, and an empty mold was used as a control. Each group was further divided into two subgroups (1 and 2) according to the material studied. The samples in groups A, B and C were transferred into synthetic tissue fluid buffered at pH values of 7.4, 4.4 and 10.4, respectively, and kept in an incubator at 37°C with 100% humidity. Daily solubility at 1-, 2-, 5-, 14-, 21-, and 30-day intervals and cumulative solubility up to 5-, 14-, and 30-day intervals were calculated. Statistical analysis was carried out with independent-samples t-test, two-way ANOVA and post hoc Tukey tests using SPSS 18. Statistical significance was set at P<0.05. Both WMTA and BD exhibited the highest solubility in acidic pH with 5.4235±0.1834 and 10.7516±0.0639 mean cumulative solubility values at 30-day interval, respectively. At all exposure times, BD was significantly more soluble than WMTA (P<0.001). Acidic periapical environment jeopardized the solubility of both WMTA and BD, affecting their sealing characteristics in clinical applications like perforation repair procedures and blunderbuss canals.
本研究旨在评估酸性、中性和碱性环境对白色矿物三氧化物聚合体（WMTA）和生物陶瓷（BD）溶解性的影响。39个环形模具被随机分为A、B、C三组（n = 12），其pH值分别为7.4、4.4和10.4，并用一个空模具作为对照。根据所研究的材料，每组进一步分为两个亚组（1和2）。将A、B、C组的样品分别转移到pH值为7.4、4.4和10.4的合成组织液中，并在37°C、湿度100%的培养箱中保存。计算1天、2天、5天、14天、21天和30天间隔的每日溶解度以及5天、14天和30天间隔的累积溶解度。使用SPSS 18进行独立样本t检验、双向方差分析和事后Tukey检验。统计学显著性设定为P<0.05。WMTA和BD在酸性pH值下的溶解度最高，在30天间隔时平均累积溶解度值分别为5.4235±0.1834和10.7516±0.0639。在所有暴露时间，BD的溶解度均显著高于WMTA（P<0.001）。根尖酸性环境会危及WMTA和BD的溶解度，影响它们在穿孔修复程序和喇叭形根管等临床应用中的封闭特性。
