Akchurin Oleh M
Weill Cornell Medical College (Pediatric Nephrology), 525 E 68th Street, Box 176, New York, NY 10065, USA.
Pediatr Clin North Am. 2019 Feb;66(1):247-267. doi: 10.1016/j.pcl.2018.09.007.
Chronic kidney disease is an ongoing deterioration of renal function that often progresses to end-stage renal disease. Management goals in children include slowing disease progression, prevention and treatment of complications, and optimizing growth, development, and quality of life. Nutritional management is critically important to achieve these goals. Control of blood pressure, proteinuria, and metabolic acidosis with dietary and pharmacologic measures may slow progression of chronic kidney disease. Although significant progress in management has been made, further research is required to resolve many outstanding controversies. We review recent developments in pediatric chronic kidney disease, focusing on dietary measures to improve outcomes.
慢性肾脏病是肾功能的持续恶化,常进展至终末期肾病。儿童慢性肾脏病的管理目标包括减缓疾病进展、预防和治疗并发症,以及优化生长发育和生活质量。营养管理对于实现这些目标至关重要。通过饮食和药物措施控制血压、蛋白尿和代谢性酸中毒可能会减缓慢性肾脏病的进展。尽管在管理方面已取得显著进展,但仍需要进一步研究来解决许多悬而未决的争议。我们回顾了儿童慢性肾脏病的最新进展,重点关注改善预后的饮食措施。