人类月经血：再生医学中可再生和可持续的干细胞来源。
Human menstrual blood: a renewable and sustainable source of stem cells for regenerative medicine.
机构信息
Department of Obstetrics and Gynecology, Nanjing Drum Tower Hospital, Graduate School of Peking Union Medical College, 321 Zhongshan Road, Nanjing, China.
Tissue Engineering Group, Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, ORCRB, Roosevelt Drive, Headington, Oxford, OX3 7DQ, UK.
出版信息
Stem Cell Res Ther. 2018 Nov 21;9(1):325. doi: 10.1186/s13287-018-1067-y.
Abstract
Stem cells (SCs) play an important role in autologous and even allogenic applications. Menstrual blood discharge has been identified as a valuable source of SCs which are referred to as menstrual blood-derived stem cells (MenSCs). Compared to SCs from bone marrow and adipose tissues, MenSCs come from body discharge and obtaining them is non-invasive to the body, they are easy to collect, and there are no ethical concerns. There is, hence, a growing interest in the functions of MenSCs and their potential applications in regenerative medicine. This review presents recent progress in research into MenSCs and their potential application. Clinical indications of using MenSCs for various regenerative medicine applications are emphasized, and future research is recommended to accelerate clinical applications of MenSCs.
摘要
干细胞（SCs）在自体甚至同种异体应用中发挥着重要作用。经血已被确定为干细胞的宝贵来源，这些干细胞被称为月经血源性干细胞（MenSCs）。与骨髓和脂肪组织来源的干细胞相比，MenSCs 来自人体分泌物，获取它们对人体无创伤，易于采集，并且不存在伦理问题。因此，人们对 MenSCs 的功能及其在再生医学中的潜在应用越来越感兴趣。本综述介绍了 MenSCs 的研究进展及其潜在应用。强调了 MenSCs 在各种再生医学应用中的临床适应证，并建议开展未来研究以加速 MenSCs 的临床应用。
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