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Vaginal Infections of Albanian women Infected with HPV and their impact in intraepithelial cervical lesions evidenced by Pap test.阿尔巴尼亚感染人乳头瘤病毒（HPV）的女性的阴道感染情况及其通过巴氏试验证明对宫颈上皮内病变的影响。
J Cytol. 2017 Jan-Mar;34(1):16-21. doi: 10.4103/0970-9371.197592.
2
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J Turk Ger Gynecol Assoc. 2013 Mar 1;14(1):23-7. doi: 10.5152/jtgga.2013.06. eCollection 2013.
3
HPV types in Turkey: multicenter hospital based evaluation of 6388 patients in Turkish gynecologic oncology group centers.土耳其的人乳头瘤病毒类型：基于土耳其妇科肿瘤学组中心6388例患者的多中心医院评估
Turk Patoloji Derg. 2013;29(3):210-6. doi: 10.5146/tjpath.2013.01188.
4
The role of co-factors in the progression from human papillomavirus infection to cervical cancer.辅助因子在人乳头瘤病毒感染向宫颈癌进展中的作用。
Gynecol Oncol. 2013 Feb;128(2):265-70. doi: 10.1016/j.ygyno.2012.11.003. Epub 2012 Nov 10.
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Genital human papillomavirus infection and genotype prevalence among Albanian women: a cross-sectional study.阿尔巴尼亚女性的生殖器人乳头瘤病毒感染和基因型流行情况：一项横断面研究。
J Med Virol. 2010 Jul;82(7):1192-6. doi: 10.1002/jmv.21803.
6
Human papillomavirus (HPV) prevalence and types among Turkish women at a gynecology outpatient unit.土耳其妇科门诊女性的人乳头瘤病毒（HPV）流行率和类型。
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Prevalence of human papillomavirus genotypes in women from a rural region of Puebla, Mexico.墨西哥普埃布拉农村地区女性人乳头瘤病毒基因型的流行情况。
Int J Infect Dis. 2009 Nov;13(6):690-5. doi: 10.1016/j.ijid.2008.10.010. Epub 2009 Jan 14.
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Worldwide prevalence and genotype distribution of cervical human papillomavirus DNA in women with normal cytology: a meta-analysis.细胞学正常女性宫颈人乳头瘤病毒DNA的全球流行率及基因型分布：一项荟萃分析
Lancet Infect Dis. 2007 Jul;7(7):453-9. doi: 10.1016/S1473-3099(07)70158-5.
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The relationship between human papillomavirus infection and cervical intraepithelial neoplasia in Turkish women.土耳其女性中人乳头瘤病毒感染与宫颈上皮内瘤变的关系。
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土耳其和阿尔巴尼亚女性人乳头瘤病毒类型的流行情况

Prevalence of Human Papilloma Virus Types in Turkish and Albanian Women.

作者信息

Hancer Veysel Sabri, Buyukdogan Murat, Bylykbashi Ilta, Oksuz Burcu, Acar Muradiye

机构信息

Department of Medical Genetics, Faculty of Medicine, Istinye University, Istanbul, Turkey.

Department of Obstetrics and Gynaecology, Queen Geraldine Univeristy Hospital, Tirana, Albania.

出版信息

J Cytol. 2018 Oct-Dec;35(4):252-254. doi: 10.4103/JOC.JOC_162_17.

DOI:10.4103/JOC.JOC_162_17
PMID:30498300
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6210813/
Abstract

BACKGROUND

Human papilloma virus (HPV) infection is the major etiologic agent of cervical carcinoma. The aim of this study was to determine the prevalence of HPV infection and genotype distribution in cervical swabs from 2,234 Turkish and 357 Albanian women with similar lifestyles from two different countries.

MATERIALS AND METHODS

HPV detection and typing were performed by type specific multiplex fluorescent PCR and fragments were directly genotyped by high resolution fluorescence capillary electrophoresis.

RESULTS

The most common type was HPV 16 and the second one was HPV 6 for both country. The third common type was 39 and 18 for Turkish and Albanian women, respectively.

CONCLUSIONS

When we compare our results with other studies, there are differences between the frequency and order of the HPV genotypes detected at the second and subsequent frequencies. This may due to differences in the quality and type of samples analyzed, as well as the HPV detection methods.

摘要

背景

人乳头瘤病毒（HPV）感染是宫颈癌的主要病因。本研究旨在确定来自两个不同国家、生活方式相似的2234名土耳其女性和357名阿尔巴尼亚女性宫颈拭子中HPV感染的患病率及基因型分布。

材料与方法

采用型特异性多重荧光PCR进行HPV检测和分型，并通过高分辨率荧光毛细管电泳直接对片段进行基因分型。

结果

两个国家最常见的类型均为HPV 16，第二常见的类型均为HPV 6。土耳其女性中第三常见的类型为HPV 39，阿尔巴尼亚女性中第三常见的类型为HPV 18。

结论

当我们将我们的结果与其他研究进行比较时，在第二及后续频率检测到的HPV基因型的频率和顺序存在差异。这可能是由于所分析样本的质量和类型以及HPV检测方法的差异所致。