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Short Term Hyperthermia Prevents Activation of Proinflammatory Genes in Type B Synoviocytes by Blocking the Activation of the Transcription Factor NF-κB.短期热疗通过阻断转录因子NF-κB的激活来防止B型滑膜细胞中促炎基因的激活。
EJIFCC. 2007 Dec 21;18(4):121-125. eCollection 2007 Dec.
2
Fibromyalgia with severe forms of progression in a multidisciplinary therapy setting with emphasis on hyperthermia therapy--a prospective controlled study.在多学科治疗环境中，以热疗为重点治疗严重进展型纤维肌痛——一项前瞻性对照研究。
Clin Interv Aging. 2014 Dec 19;10:69-79. doi: 10.2147/CIA.S74949. eCollection 2015.
3
Whole body hyperthermia treatment increases interleukin 10 and toll-like receptor 4 expression in patients with ankylosing spondylitis: a pilot study.全身热疗增加强直性脊柱炎患者白细胞介素10和Toll样受体4表达：一项初步研究。
Int J Hyperthermia. 2014 Sep;30(6):393-401. doi: 10.3109/02656736.2014.956810.
4
The role of hyperthermia in the battle against cancer.
Tumori. 2010 Nov-Dec;96(6):902-10.
5
Short term hyperthermia prevents the activation of mitogen-activated protein kinase p38.短期热疗可阻止丝裂原活化蛋白激酶 p38 的激活。
Exp Gerontol. 2009 Jun-Jul;44(6-7):406-12. doi: 10.1016/j.exger.2009.03.002. Epub 2009 Mar 17.
6
The effect of mild whole-body hyperthermia on systemic levels of TNF-alpha, IL-1beta, and IL-6 in patients with ankylosing spondylitis.轻度全身热疗对强直性脊柱炎患者体内肿瘤坏死因子-α、白细胞介素-1β和白细胞介素-6系统水平的影响。
Clin Rheumatol. 2009 Apr;28(4):397-402. doi: 10.1007/s10067-008-1059-x. Epub 2008 Dec 17.
7
Hyperthermia induced by microwave diathermy in the management of muscle and tendon injuries.微波透热疗法诱导的高热在肌肉和肌腱损伤治疗中的应用
Br Med Bull. 2007;83:379-96. doi: 10.1093/bmb/ldm020.
8
A randomized controlled trial on the effectiveness of mild water-filtered near infrared whole-body hyperthermia as an adjunct to a standard multimodal rehabilitation in the treatment of fibromyalgia.一项关于轻度水过滤近红外全身热疗作为标准多模式康复辅助手段治疗纤维肌痛有效性的随机对照试验。
Clin J Pain. 2007 Jan;23(1):67-75. doi: 10.1097/AJP.0b013e31802b4f80.
9
Short-term effectiveness of hyperthermia for supraspinatus tendinopathy in athletes: a short-term randomized controlled study.热疗对运动员冈上肌腱病的短期疗效：一项短期随机对照研究。
Am J Sports Med. 2006 Aug;34(8):1247-53. doi: 10.1177/0363546506287827. Epub 2006 Apr 24.
10
Thermal signature analysis as a novel method for evaluating inflammatory arthritis activity.热特征分析作为评估炎性关节炎活动度的一种新方法。
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风湿性疾病中的热疗。一种有前景的方法？

Hyperthermia in rheumatic diseases. A promising approach?

作者信息

Jeziorski Krzysztof

机构信息

Department of Gerontology, Public Health, and Didactics, National Institute of Geriatrics, Rheumatology, and Rehabilitation, Warsaw, Poland.

Maria Sklodowska-Curie Memorial Cancer Centre and Institute of Oncology, Warsaw, Poland.

出版信息

Reumatologia. 2018;56(5):316-320. doi: 10.5114/reum.2018.79503. Epub 2018 Oct 31.

DOI:10.5114/reum.2018.79503
PMID:30505014
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6263304/
Abstract

Hyperthermia is a method applied in the treatment of many diseases, including rheumatic diseases. There are relatively few reports concerning the role of that method in the treatment of these diseases, and most studies have not been randomised. Hyperthermia includes directed application of thermal energy. The aim of that therapy is to overcome the body's natural thermoregulation mechanism through application of external heat sources such as electromagnetic radiation of various frequencies, or ultrasound. Usually, temperatures are used within the 38.5-43° range. Hyperthermia can be applied as topical, regional, or systemic treatment (the latter is called hyperthermia of the whole body). In rheumatology, mainly the effect of hyperthermia on the immune system of the body is used. That effect depends on the type of hyperthermia and temperatures applied. Best documented are the effects of hyperthermia in fibromyalgia and ankylosing spondylitis.

摘要

热疗是一种应用于多种疾病治疗的方法，包括风湿性疾病。关于该方法在这些疾病治疗中的作用的报道相对较少，并且大多数研究并非随机研究。热疗包括定向施加热能。该疗法的目的是通过应用各种频率的电磁辐射或超声波等外部热源来克服人体的自然体温调节机制。通常，使用的温度范围在38.5至43摄氏度之间。热疗可作为局部、区域或全身治疗（后者称为全身热疗）应用。在风湿病学中，主要利用热疗对人体免疫系统的作用。该作用取决于热疗的类型和所应用的温度。热疗在纤维肌痛和强直性脊柱炎中的作用记录最为充分。