Koelbl Philipp S, Hessling Martin, Lingenfelder Christian, Kupferschmid Sebastian
Institute of Medical Engineering and Mechatronics, Ulm University of Applied Sciences, Albert-Einstein-Allee 55, 89081, Ulm, Germany.
Medical Faculty, Ulm University, Albert-Einstein-Allee 7, 89081, Ulm, Germany.
Ophthalmol Ther. 2019 Mar;8(1):41-50. doi: 10.1007/s40123-018-0157-3. Epub 2018 Dec 17.
All applied illumination systems are validated according to a standard that measures in an experimental setup the direct radiation intensity on a surface in an aqueous solution, not involving an eyeball. Due to various factors, multiple intraocular light-tissue interactions could occur and lead to retinal irradiation intensities that are higher than the irradiation caused by direct illumination. The aim of this work is to investigate the hypothesis that intraocular and technical reference irradiance is different.
Using an illumination system and a calibrated optical fiber, the irradiance in porcine eyes was measured at the posterior pole (macula) and compared with reference measurements. We compared two endoilluminators (spotlight and wide-angle) at a total of nine porcine eyes with a brown iris and five porcine eyes with a blue iris.
The intraocular irradiance was always significantly higher compared to reference measurements (p < 0.001). Between eyes with a blue or brown iris, no significant difference was observed.
A significantly higher irradiance could be measured compared to a reference measurement with the same illumination setup. The intraocular illumination increased between 30 and 60%, dependent on the distance of the distal end of the light fiber (4-12-mm distance to the retina). This leads to the assumption that the so far allowed "safe" exposure times for illumination systems are overestimated and the potential hazard to the retina is higher.
所有应用的照明系统均按照一项标准进行验证，该标准在不涉及眼球的实验装置中测量水溶液表面的直接辐射强度。由于各种因素，眼内会发生多种光与组织的相互作用，导致视网膜照射强度高于直接照明所引起的照射强度。本研究的目的是探讨眼内照射与技术参考照射不同这一假设。
使用照明系统和校准光纤，在猪眼后极（黄斑）测量辐照度，并与参考测量值进行比较。我们比较了两种眼内照明器（聚光灯和广角照明器），共测量了9只棕色虹膜猪眼和5只蓝色虹膜猪眼。
与参考测量相比，眼内辐照度始终显著更高（p < 0.001）。在蓝色或棕色虹膜的眼睛之间，未观察到显著差异。
与相同照明设置的参考测量相比，可测量到显著更高的辐照度。眼内照明增加了30%至60%，这取决于光纤远端到视网膜的距离（距视网膜4 - 12毫米的距离）。这导致人们认为，迄今为止照明系统允许的“安全”暴露时间被高估了，对视网膜的潜在危害更大。
