Department of Dermatology and Venereology, Skåne University Hospital, Malmo, Sweden.
National Centre for Dual Diagnosis, Innlandet Hospital Trust, Brumunddal, Norway.
BMJ Open. 2018 Dec 22;8(12):e024877. doi: 10.1136/bmjopen-2018-024877.
Patients with common skin diseases may have substantial psychosocial comorbidity and reduced quality of life. This study aims at exploring further the psychosocial burden of skin diseases by assessing stigmatisation and body image problems in a large sample of patients with skin disease across Europe.
The study is an observational cross-sectional multicentre study across 16 European countries comparing stigmatisation and body image in patients with skin disease compared with controls. Consecutive patients will be recruited in outpatient clinics and will complete validated questionnaires prior to clinical examination by a dermatologist at each recruitment site. In addition to sociodemographic background information, the outcomes will be: mood disorders assessed by short versions of the Patient Health Questionnaire and the General Anxiety Disorder Assessment; general health assessed by the EuroQol-Visual Analogue Scale; stigmatisation experience assessed by the Perceived Stigmatisation Questionnaire; stress assessed by the Perceived Stress Scale and body image assessed by the Dysmorphic Concern Questionnaire. The main criteria for eligibility are to be 18 years old or more. The analysis will include comparison between patients and controls for the main outcomes using t-tests, analyses of covariance and multivariate logistic regression models adjusting for potential confounding factors.
The study protocol is approved by the University of Giessen and by the local Ethical Committee in each recruitment centre. Informed consent will be given by each participant. The results of the study will be disseminated by publications in international peer-reviewed journals and presented at international conferences and general public conferences. Results will influence support intervention and management of patients with skin disease across Europe.
DRKS00012745; Pre-results.
患有常见皮肤病的患者可能存在较大的心理社会共病和生活质量下降。本研究旨在通过评估欧洲多个国家/地区的大量皮肤病患者的污名化和身体意象问题，进一步探索皮肤病的心理社会负担。
这是一项在欧洲 16 个国家进行的观察性横断面多中心研究，比较了皮肤病患者与对照组的污名化和身体意象。将连续招募门诊患者，并在每个招募地点由皮肤科医生进行临床检查之前，填写经过验证的问卷。除了社会人口统计学背景信息外，结果还将包括：使用患者健康问卷和广泛性焦虑症评估的简短版本评估心境障碍；使用 EuroQol-视觉模拟量表评估一般健康状况；使用感知污名问卷评估污名化体验；使用感知压力量表评估压力和使用畸形关注问卷评估身体意象。主要入选标准为 18 岁或以上。分析将包括使用 t 检验、协方差分析和多元逻辑回归模型对主要结局在患者和对照组之间进行比较，调整潜在混杂因素。
该研究方案已获得吉森大学和每个招募中心的当地伦理委员会的批准。每个参与者都将给予知情同意。研究结果将通过在国际同行评议期刊上发表文章、在国际会议和公众会议上展示来传播。研究结果将影响整个欧洲对皮肤病患者的支持干预和管理。
DRKS00012745；预结果。
