Naiktari Ritam Sanvala, Dharmadhikari Chandrakant, Gurav Abhijit Ningappa, Kakade Satish
Department of Periodontics, Goa Dental College and Hospital, Bambolim, Goa, India.
Department of Microbiology, Tatyasaheb Kore Dental College and Research Centre, Kolhapur, Maharashtra, India.
J Indian Soc Periodontol. 2018 Nov-Dec;22(6):498-502. doi: 10.4103/jisp.jisp_265_18.
Triphala has been extensively used in dentistry as a mouthwash because of its antiplaque and antigingivitis properties.
The present study is designed to determine the duration of its antibacterial substantivity after a single oral rinse and to compare it with the substantivity of 0.2% chlorhexidine gluconate (CHX).
In this clinical crossover trial, unstimulated saliva from 30 individuals was collected 2 h after routine oral hygiene procedures but not rinsing (pre-sample) with randomly selected mouthwash, (10% Triphala mouthwash, 0.2% CHX, and normal saline) and 5 min after rinsing (postsample). A washout period of 1 week was kept between two rinses. The sampling was repeated after every 2 h for 12 h (post 1, post 2, post 3, post 4, post 5, and post 6) and was checked for microbial count.
Friedman test, Kruskal-Wallis test, and analysis were used to assess the effect of different mouthrinses on colony forming units at different times.
Ten percent Triphala showed statistically significant results when the antibacterial effect at post, post 1 and post 2 were compared to pre-assessment count ( < 0.05). After which the effect was at par with normal saline ( > 0.05). The results for CHX were statistically significant at all times when compared to pre-assessment count ( < 0.05) and it showed the maximum substantivity of 7 h.
After a single rinse with no eating and drinking restrictions over the day, 10% Triphala mouthwash had an antibacterial effect for 3-4 h. It can be used three times daily for its maximum antibacterial effect.
由于具有抗牙菌斑和抗牙龈炎的特性，三果木在牙科领域被广泛用作漱口水。
本研究旨在确定单次口腔冲洗后其抗菌持续性的时长，并将其与0.2%葡萄糖酸氯己定（CHX）的持续性进行比较。
在这项临床交叉试验中，30名个体在进行常规口腔卫生程序但未漱口（预样本）后2小时，随机选用漱口水（10%三果木漱口水、0.2% CHX和生理盐水），漱口后5分钟收集非刺激性唾液。两次漱口之间保持1周的洗脱期。每隔2小时重复采样，共12小时（第1次采样后、第2次采样后、第3次采样后、第4次采样后、第5次采样后和第6次采样后），并检查微生物数量。
采用Friedman检验、Kruskal-Wallis检验和分析来评估不同漱口水在不同时间对菌落形成单位的影响。
当将第1次采样后、第2次采样后的抗菌效果与预评估计数进行比较时，10%三果木漱口水显示出统计学上的显著结果（P<0.05）。此后，其效果与生理盐水相当（P>0.05）。与预评估计数相比，CHX在所有时间的结果均具有统计学显著性（P<0.05），并且其显示出最长7小时的持续性。
在一天内单次冲洗且无饮食限制的情况下，10%三果木漱口水具有3至4小时的抗菌效果。为达到最大抗菌效果，可每日使用三次。
