母乳在不同泌乳阶段的三酰甘油组成。

Triacylglycerol Composition of Breast Milk during Different Lactation Stages.

机构信息

Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province, School of Food Science and Technology , Jiangnan University , Wuxi 214122 , P. R. China.

College of Food Science and Technology , Henan University of Technology , Lianhua Street 100 , Zhengzhou 450001 , P. R. China.

出版信息

J Agric Food Chem. 2019 Feb 27;67(8):2272-2278. doi: 10.1021/acs.jafc.8b06554. Epub 2019 Feb 14.

DOI:10.1021/acs.jafc.8b06554

PMID:30706708

Abstract

Triacylglycerol (TAG) composition of breast milk plays an important role in improving digestion, absorption, and metabolism when consumed by infants. This study characterized the TAG profile of human colostrum, transitional, and mature milk samples from 103 women. Significant differences in the TAGs composition of breast milk fat from three lactation stages were observed. The TAGs with high molecular weight and unsaturated fatty acid (such as 1,3-olein-2-palmitin (OPO) and 1(3)-olein-2-palmitin-3(1)-linolein (OPL)) were enriched in colostrum, while the TAGs containing medium-chain fatty acids were more abundant in transitional and mature milk than that in colostrum. Of note, OPL was the most common TAG in breast milk of Chinese women while the most common TAG in breast milk of Western women was OPO. This data will promote the development of infant formulas in terms of the TAG composition more suitable for infants.

摘要

母乳中的三酰甘油（TAG）组成在婴儿食用时对于改善消化、吸收和代谢起着重要作用。本研究对 103 位女性的人初乳、过渡乳和成熟乳样本中的 TAG 谱进行了特征分析。观察到三种泌乳阶段母乳脂肪中 TAG 组成存在显著差异。高分子量和不饱和脂肪酸的 TAG（如 1,3-油酰-2-棕榈酸甘油酯（OPO）和 1(3)-油酰-2-棕榈酸甘油酯-3(1)-亚油酸甘油酯（OPL））在初乳中丰富，而含有中链脂肪酸的 TAG 在过渡乳和成熟乳中的含量高于初乳。值得注意的是，OPL 是中国女性母乳中最常见的 TAG，而西方女性母乳中最常见的 TAG 是 OPO。这些数据将促进更适合婴儿的 TAG 组成的婴儿配方奶粉的开发。