Omotayo Oluwadara Pelumi, Omotayo Abiodun Olusola, Mwanza Mulunda, Babalola Olubukola Oluranti
Department of Biological Sciences, Faculty of Natural and Agricultural Science, North-West University, Mmabatho, South Africa.
Food Security and Safety Niche, Faculty of Natural and Agricultural Science, North-West University, Mafikeng Campus, Mmabatho, South Africa.
Toxicol Res. 2019 Jan;35(1):1-7. doi: 10.5487/TR.2019.35.1.001. Epub 2018 Jan 15.
Mycotoxin contamination is a global phenomenon and causes a wide array of negative effects and other complications. This study focused on commonly found mycotoxins in Africa and the possible means of prevention or reduction of their contaminating effects. Mycotoxins are secondary metabolites of mold and fungi; they are generally toxic to living organisms. Hundreds of mycotoxins have been identified thus far, with some, such as aflatoxins, ochratoxins, trichothecenes, zearalenone, fumonisins, and patulin, considered agro-economically important. Several factors contribute to the presence of mycotoxins in food, such as climatic conditions, pest infestation, and poor harvest and storage practices. Exposure to mycotoxins, which occurs mostly by ingestion, leads to various diseases, such as mycotoxicoses and mycoses that may eventually result in death. In light of this, this review of relevant literature focuses on mycotoxin contamination, as well as various methods for the prevention and control of their prevalence, to avert its debilitating consequences on human health. Clear evidence of mycotoxin contamination is present in Africa, and it was therefore recommended that adequate prevention and control of these toxic substances in our food system should be encouraged and that appropriate measures must be taken to ensure food safety as well as the enhanced or long-lifespan of the African populace. Governments, research institutions, and non-governmental organizations should tailor the limited resources available to tackle mycotoxin prevalence, as these will offer the best prospects for successful development of a sustainable food system in Africa.
霉菌毒素污染是一个全球现象,会造成一系列负面影响及其他并发症。本研究聚焦于非洲常见的霉菌毒素以及预防或降低其污染影响的可能方法。霉菌毒素是霉菌和真菌的次生代谢产物;它们通常对生物体有毒。迄今为止,已鉴定出数百种霉菌毒素,其中一些,如黄曲霉毒素、赭曲霉毒素、单端孢霉烯族毒素、玉米赤霉烯酮、伏马菌素和展青霉素,被认为具有农业经济重要性。食物中霉菌毒素的存在受多种因素影响,如气候条件、虫害以及收获和储存方式不当。接触霉菌毒素主要通过摄入发生,会导致各种疾病,如霉菌毒素中毒和真菌病,最终可能导致死亡。有鉴于此,本相关文献综述聚焦于霉菌毒素污染以及预防和控制其流行的各种方法,以避免其对人类健康造成的不利后果。非洲存在霉菌毒素污染的明确证据,因此建议鼓励在我们的食物系统中对这些有毒物质进行充分的预防和控制,并必须采取适当措施确保食品安全以及提高非洲民众的寿命或延长其寿命。政府、研究机构和非政府组织应合理调配有限资源以应对霉菌毒素的流行,因为这些将为非洲可持续食物系统的成功发展提供最佳前景。