Park Chul Soon, Lee Changsoo, Kwon Oh Seok
Hazards Monitoring Bionano Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon 34141, Korea.
Nanobiotechnology and Bioinformatics, University of Science & Technology (UST), 125 Gwahak-ro, Yuseong-gu, Daejeon 34144, Korea.
Polymers (Basel). 2016 Jun 30;8(7):249. doi: 10.3390/polym8070249.
In recent years, conducting polymer (CP) nanomaterials have been used in a variety of fields, such as in energy, environmental, and biomedical applications, owing to their outstanding chemical and physical properties compared to conventional metal materials. In particular, nanobiosensors based on CP nanomaterials exhibit excellent performance sensing target molecules. The performance of CP nanobiosensors varies based on their size, shape, conductivity, and morphology, among other characteristics. Therefore, in this review, we provide an overview of the techniques commonly used to fabricate novel CP nanomaterials and their biosensor applications, including aptasensors, field-effect transistor (FET) biosensors, human sense mimicking biosensors, and immunoassays. We also discuss prospects for state-of-the-art nanobiosensors using CP nanomaterials by focusing on strategies to overcome the current limitations.
近年来，导电聚合物（CP）纳米材料因其与传统金属材料相比具有出色的化学和物理性质，已被应用于能源、环境和生物医学等多个领域。特别是，基于CP纳米材料的纳米生物传感器在检测目标分子方面表现出优异性能。CP纳米生物传感器的性能因其尺寸、形状、导电性和形态等特性而有所不同。因此，在本综述中，我们概述了用于制备新型CP纳米材料的常用技术及其生物传感器应用，包括适体传感器、场效应晶体管（FET）生物传感器、仿生生物传感器和免疫测定。我们还通过关注克服当前局限性的策略，讨论了使用CP纳米材料的先进纳米生物传感器的前景。
