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将酰胺酶固定在磁性分级多孔金属有机骨架中用于高效生物催化。

Immobilization of amidase into a magnetic hierarchically porous metal-organic framework for efficient biocatalysis.

机构信息

Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310014, China.

出版信息

Chem Commun (Camb). 2019 May 14;55(40):5697-5700. doi: 10.1039/c9cc02038a.

DOI:10.1039/c9cc02038a
PMID:31032825
Abstract

A novel magnetic hierarchically porous metal-organic framework (MOF) has been successfully fabricated via a modulator-induced defect-formation strategy. Amidase for the first time has been immobilized into this magnetic carrier and the resultant bio-composite exhibits superior enzymatic catalysis performance compared to the free enzyme and its counterparts without hierarchical porosity.

摘要

一种新型的磁性分级多孔金属有机骨架(MOF)通过调节剂诱导缺陷形成策略成功制备。酰胺酶首次被固定在这种磁性载体中,与游离酶及其无分级多孔结构的对应物相比,所得的生物复合材料表现出优异的酶催化性能。

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