Casal M J, Rodriguez F C, Luna M D, Benavente M C
Antimicrob Agents Chemother. 1987 Jan;31(1):132-3. doi: 10.1128/AAC.31.1.132.
The in vitro susceptibility of Mycobacterium tuberculosis, Mycobacterium bovis, Mycobacterium africanum, Mycobacterium avium, Mycobacterium fortuitum, and Mycobacterium chelonae (M. chelonei) to ticarcillin in combination with calvulanic acid (CA) was studied by the agar dilution method. All the M. tuberculosis, M. bovis, and M. africanum strains were inhibited at a ticarcillin concentration of 32 micrograms/ml or lower in combination with 5 micrograms of CA. M. chelonae and M. avium strains proved resistant to more than 128 micrograms of ticarcillin plus 5 micrograms of CA per ml. M. fortuitum strains needed 128 micrograms of ticarcillin plus 5 micrograms of CA to inhibit approximately 30% of the isolates.
采用琼脂稀释法研究了结核分枝杆菌、牛分枝杆菌、非洲分枝杆菌、鸟分枝杆菌、偶然分枝杆菌和龟分枝杆菌(龟分枝杆菌)对替卡西林联合克拉维酸(CA)的体外敏感性。所有结核分枝杆菌、牛分枝杆菌和非洲分枝杆菌菌株在替卡西林浓度为32微克/毫升或更低且联合5微克CA时均受到抑制。龟分枝杆菌和鸟分枝杆菌菌株对每毫升超过128微克的替卡西林加5微克CA表现出耐药性。偶然分枝杆菌菌株需要128微克的替卡西林加5微克CA才能抑制约30%的分离株。