Pontes Eveline Kelle Ursulino, Melo Hider Machado, Nogueira José Walter Araújo, Firmino Nairley Cardoso Sá, de Carvalho Mário Geraldo, Catunda Júnior Francisco Eduardo Aragão, Cavalcante Theodora Thays Arruda
Health Sciences Center, University Center UNINTA, Sobral, CE 62050-100 Brazil.
Medical Sciences Center, University Center UNINTA, Sobral, CE 62050-100 Brazil.
Food Sci Biotechnol. 2018 Oct 30;28(3):633-639. doi: 10.1007/s10068-018-0502-2. eCollection 2019 Jun.
Medicinal plants with antimicrobial action have been investigated for uses against biofilms, among which, , citronella, stands out as a promising species. The present study aims to evaluate the antimicrobial and antibiofilm action of the essential oil of (EOCN) and geraniol on Gram-negative and positive bacteria from the determination of minimum inhibitory concentration (MIC) and minimum bactericidal concentration and inhibition of biofilms. In the results, the EOCN produced a 41 mm halo on , which was susceptible with MIC values of 0.5 and 0.25 mg/mL for the EOCN and geraniol respectively, both with bactericidal effect. The antibiofilm action was confirmed, the EOCN and geraniol reduced the biofilm biomass of up to 100% between 0.5 and 4 mg/mL concentrations. The reduction of cell viability was 0.25 and 1 mg/mL, of EOCN and geraniol, respectively. EOCN and geraniol were shown to be promising antibiotic against
具有抗菌作用的药用植物已被研究用于对抗生物膜,其中香茅表现为一种有前景的物种。本研究旨在通过测定最低抑菌浓度(MIC)、最低杀菌浓度以及生物膜抑制情况,评估香茅精油(EOCN)和香叶醇对革兰氏阴性菌和阳性菌的抗菌及抗生物膜作用。结果显示,EOCN在金黄色葡萄球菌上产生了41毫米的抑菌圈,该菌对EOCN和香叶醇敏感,其MIC值分别为0.5和0.25毫克/毫升,二者均有杀菌作用。抗生物膜作用得到证实,EOCN和香叶醇在0.5至4毫克/毫升浓度之间可将金黄色葡萄球菌的生物膜生物量降低多达100%。EOCN和香叶醇使细胞活力降低的浓度分别为0.25和1毫克/毫升。EOCN和香叶醇被证明是有前景的抗生素,可对抗…… (原文此处不完整)