School of Plant Protection, Anhui Agricultural University, Hefei 230036, China.
Institute of Plant Protection and Agro-Product Safety, Anhui Academy of Agricultural Sciences, Key Laboratory of Agro-Product Safety Risk Evaluation (Hefei), Ministry of Agriculture, Hefei 230031, China.
Int J Environ Res Public Health. 2019 Jun 21;16(12):2196. doi: 10.3390/ijerph16122196.
Before being administered as medicinal products, Chinese herbal medicines (CHMs) must be processed and decocted for human consumption. While the presence of pesticide residues in CHMs is a major concern, pesticide dissipation behavior during CHM processing has rarely been reported. In this study, the dissipation of three pesticide residues in the CHM Alba (PRA) was investigated during each step of industrial processing. The boiling process was found to significantly reduce pesticide residues (61-89%), and the peeling process also contributed to pesticide degradation (29-68%). The high temperature (60 °C) during the drying process led to further pesticide degradation. The processing factors of all three pesticides after each processing step were less than one, and the processing factors for the overall process were lower than 0.027, indicating that industrial processing clearly reduced the amount of pesticide residues (97.3-99.4%). The findings provide guidance for the safe use of fungicides in CHMs and can help establish maximum residue limits for PRA to reduce human exposure to pesticides.
中药材在作为药品使用之前，必须经过加工和煎煮才能供人类食用。虽然中药材中存在农药残留是一个主要关注点，但中药材加工过程中农药的消解行为却很少有报道。在这项研究中，研究了工业加工过程中每一步中中药白芍（PRA）中三种农药残留的消解情况。结果发现，煮沸过程显著降低了农药残留（61-89%），去皮过程也有助于农药降解（29-68%）。干燥过程中的高温（60°C）导致进一步的农药降解。三种农药在每一步加工后的加工系数均小于 1，整个过程的加工系数均低于 0.027，表明工业加工明显减少了农药残留量（97.3-99.4%）。这些发现为中药材中使用杀菌剂提供了安全使用的指导，并有助于为 PRA 建立最大残留限量，以减少人类接触农药。
