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埃塞俄比亚的糖尿病视网膜病变:一项系统评价与荟萃分析。

Diabetic retinopathy in Ethiopia: A systematic review and meta-analysis.

作者信息

Fite Robera Olana, Lake Eyasu Alem, Hanfore Lolemo Kelbiso

机构信息

Department of Nursing, College of Health Sciences and Medicine, Wolaita Sodo University, Ethiopia.

出版信息

Diabetes Metab Syndr. 2019 May-Jun;13(3):1885-1891. doi: 10.1016/j.dsx.2019.04.016. Epub 2019 Apr 17.

DOI:10.1016/j.dsx.2019.04.016
PMID:31235110
Abstract

AIMS

this systemic review and meta-analysis was aimed at determining the level of diabetic retinopathy among diabetes mellitus patients in Ethiopia.

MATERIALS AND METHODS

PubMed, Science Direct, Google Scholar and Excerpta Medica Database (EMBASE) were searched. The data were extracted using Microsoft Excel and analyzed by using STATA version 11. Publication bias was checked by funnel plot and more objectively through Egger's regression test, with P < 0.05 considered to indicate potential publication bias. Heterogeneity of studies was checked using the I test. Pooled analysis was conducted. Subgroup analysis was done by region. Sensitivity analysis was employed to see the effect of single study on the overall estimation. STATA version 11 statistical software was used for meta-analysis.

RESULTS

The overall prevalence of retinopathy was 19.48% (95% CI: 15.95, 23.01) Based on the subgroup analysis the prevalence of retinopathy was 12.48% in SNNPR, 24.8% in Oromia, 19.99% in Amhara, and 16.29% in Addis Ababa.

CONCLUSION

The prevalence of diabetic retinopathy among Diabetes mellitus patients is high. Therefore, close monitoring of the patient prognosis and appropriate prevention techniques is essential.

摘要

目的

本系统评价和荟萃分析旨在确定埃塞俄比亚糖尿病患者中糖尿病视网膜病变的水平。

材料与方法

检索了PubMed、科学Direct、谷歌学术和医学文摘数据库(EMBASE)。使用Microsoft Excel提取数据,并使用STATA 11版进行分析。通过漏斗图检查发表偏倚,并通过Egger回归检验更客观地检查,P<0.05被认为表明存在潜在的发表偏倚。使用I检验检查研究的异质性。进行汇总分析。按地区进行亚组分析。采用敏感性分析来观察单个研究对总体估计的影响。使用STATA 11版统计软件进行荟萃分析。

结果

视网膜病变的总体患病率为19.48%(95%CI:15.95,23.01)。基于亚组分析,南方各族州人民区域州(SNNPR)的视网膜病变患病率为12.48%,奥罗米亚州为24.8%,阿姆哈拉州为19.99%,亚的斯亚贝巴为1,6.29%。

结论

糖尿病患者中糖尿病视网膜病变的患病率很高。因此,密切监测患者预后和采用适当的预防技术至关重要。

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