Department of Psychology, Michigan State University, East Lasing, MI, USA.
University of Michigan, Ann Arbor, MI, USA.
Psychol Med. 2020 Jul;50(9):1519-1529. doi: 10.1017/S0033291719001521. Epub 2019 Jul 1.
Prior work has robustly suggested that social processes in the neighborhood (i.e. informal social control, social cohesion, norms) influence child conduct problems (CP) and related outcomes, but has yet to consider how these community-level influences interact with individual-level genetic risk for CP. The current study sought to do just this, evaluating neighborhood-level social processes as etiologic moderators of child CP for the first time.
We made use of two nested samples of child and adolescent twins within the Michigan State University Twin Registry (MSUTR): 5649 families who participated in in the Michigan Twins Project (MTP) and 1013 families who participated in the Twin Study of Behavioral and Emotional Development (TBED-C). The neighborhood social processes of informal social control, social cohesion, and norms were assessed using neighborhood sampling techniques, in which residents of each twin family's neighborhood reported on the social processes in their neighborhood. Standard biometric GxE analyses evaluated the extent to which they moderated the etiology of CP.
The 'no moderation' model provided the best fit to the data in nearly all cases, arguing against neighborhood social processes as etiologic moderators of youth CP.
The neighborhood social processes evaluated here do not appear to exert their effects on child CP via etiologic moderation. The documented links between neighborhood social processes and child CP are thus likely to reflect a different etiologic process. Possibilities include environmental main effects of neighborhood social processes on child CP, or genotype-environment correlations.
先前的研究有力地表明,邻里的社会过程(即非正式社会控制、社会凝聚力、规范)会影响儿童的行为问题(CP)及相关结果,但尚未考虑这些社区层面的影响如何与儿童 CP 的个体遗传风险相互作用。本研究旨在首次评估邻里社会过程作为儿童 CP 的病因学调节因素。
我们利用密歇根州立大学双胞胎登记处(MSUTR)内的儿童和青少年双胞胎的两个嵌套样本:5649 个参与密歇根双胞胎项目(MTP)的家庭和 1013 个参与行为和情感发展双胞胎研究(TBED-C)的家庭。使用邻里抽样技术评估了非正式社会控制、社会凝聚力和规范等邻里社会过程,其中每个双胞胎家庭的居民报告了其邻里的社会过程。使用标准生物计量 GxE 分析评估了它们在多大程度上调节 CP 的病因。
在几乎所有情况下,“无调节”模型都为数据提供了最佳拟合,这表明邻里社会过程不是青年 CP 的病因学调节因素。
这里评估的邻里社会过程似乎并没有通过病因学调节来对儿童 CP 产生影响。因此,邻里社会过程与儿童 CP 之间的记录联系可能反映了不同的病因学过程。可能性包括邻里社会过程对儿童 CP 的环境主要影响,或基因型-环境相关性。