Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.
Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO, USA.
J Sci Food Agric. 2019 Dec;99(15):6663-6670. doi: 10.1002/jsfa.9903. Epub 2019 Sep 30.
There is little evidence about whether eggs affect inflammation. The aim of this meta-analysis was to explore the effects of egg consumption on inflammation. A systematic search of online databases (Institute for Scientific Information (ISI), Scopus, Ovid, PubMed, Cochrane) was used to gather clinical trials that assessed the effect of egg consumption on circulating inflammatory biomarkers. Using a random-effects model, pooled weighted mean differences (WMD) and corresponding standard deviations (SD) were calculated. Of the 21 eligible studies found, nine trials were eligible for analysis. Eight trials assessed high-sensitivity C-reactive protein (hs-CRP), four trials assessed interleukin-6 (IL-6), and five trials assessed tumor necrosis factor-alpha (TNF-α). Egg consumption did not affect hs-CRP (WMD 0.24 mg/L; 95% CI: -0.43, 0.90; I = 53.8; P = 0.48), IL-6 (WMD 0.20 pg/mL; 95% CI: -0.71, 1.11; I = 69.3; P = 0.50), and TNF-α (WMD: -0.38 pg/mL; 95% CI: -0.87, 0.10; I = 0.00; P = 0.12) relative to controls. Overall, this meta-analysis revealed that egg consumption had no significant effect on serum biomarkers of inflammation in adults. © 2019 Society of Chemical Industry.
关于鸡蛋是否会影响炎症，证据很少。本荟萃分析的目的是探讨鸡蛋摄入对炎症的影响。系统检索在线数据库（科学信息研究所（ISI）、Scopus、Ovid、PubMed、Cochrane），以收集评估鸡蛋摄入对循环炎症生物标志物影响的临床试验。使用随机效应模型，计算了合并的加权均数差值（WMD）和相应的标准差（SD）。在 21 项符合条件的研究中，有 9 项试验符合分析条件。8 项试验评估了高敏 C 反应蛋白（hs-CRP），4 项试验评估了白细胞介素 6（IL-6），5 项试验评估了肿瘤坏死因子-α（TNF-α）。鸡蛋摄入不会影响 hs-CRP（WMD 0.24 mg/L；95%CI：-0.43，0.90；I = 53.8；P = 0.48）、IL-6（WMD 0.20 pg/mL；95%CI：-0.71，1.11；I = 69.3；P = 0.50）和 TNF-α（WMD：-0.38 pg/mL；95%CI：-0.87，0.10；I = 0.00；P = 0.12）与对照组相比。总体而言，本荟萃分析表明，鸡蛋摄入对成年人血清炎症生物标志物没有显著影响。© 2019 化学工业协会。
