Department of Education, Faculty of Education Sciences, University of Almería, 04120 Almería, Spain.
SPORT Research Group (CTS-1024), CERNEP Research Center, University of Almería, 04120 Almería, Spain.
Medicina (Kaunas). 2019 Jul 3;55(7):334. doi: 10.3390/medicina55070334.
Several anthropometric and body composition parameters have been linked to arterial stiffness (AS) as a biomarker of cardiovascular disease. However, little is known about which of these closely related factors is more strongly associated with AS. The aim of the present study was to analyze the relationship of different anthropometric and body composition parameters with AS in middle-aged adults. This cross-sectional study included 186 middle-aged participants (85 women, 101 men; age = 42.8 ± 12.6 years) evaluated as part of the Healthy UAL study, a population study conducted at the University of Almería with the main purpose of analyzing the etiology and risk factors associated with cardio-metabolic diseases. Anthropometric measures included neck, waist, and hip circumferences, as well as the waist-to-height ratio (WHtr). Bioimpedance-derived parameters included fat-free mass index (FFMI), fat mass index (FMI), and percent of body fat (%BF). AS was measured by pulse wave velocity (PWV). The relationships of interest were examined through stepwise regression analyses in which age and sex were also introduced as potential confounders. Neck circumference (in the anthropometric model; : 0.889; : age = 0.855, neck = 0.204) and FFMI (in the bio-impedance model; : 0.891; : age = 0.906, FFMI = 0.199) emerged as significant cross-sectional predictors of AS. When all parameters were included together (both anthropometry and bio-impedance), both neck circumference and FFMI appeared again as being significantly associated with AS (: 0.894; : age = 0.882, FFMI = 0.126, neck = 0.093). It was concluded that FFMI and neck circumference are correlated with AS regardless of potential confounders and other anthropometric and bioimpedance-derived parameters in middle-aged adults.
几种人体测量学和身体成分参数已被证实与动脉僵硬度（AS）有关，AS 是心血管疾病的生物标志物。然而，目前对于这些密切相关的因素中哪一个与 AS 相关性更强知之甚少。本研究旨在分析中年人群中不同人体测量学和身体成分参数与 AS 的关系。
该横断面研究纳入了 186 名中年参与者（85 名女性，101 名男性；年龄=42.8±12.6 岁），他们是阿尔梅里亚大学进行的一项名为“UAL 健康”的人群研究的一部分，该研究的主要目的是分析与心血管代谢疾病相关的病因和危险因素。人体测量学指标包括颈围、腰围和臀围，以及腰高比（WHtr）。生物电阻抗衍生参数包括去脂体重指数（FFMI）、脂肪质量指数（FMI）和体脂百分比（%BF）。通过脉搏波速度（PWV）测量 AS。通过逐步回归分析来检验感兴趣的关系，其中还引入了年龄和性别作为潜在的混杂因素。
颈围（在人体测量模型中；：0.889；：年龄=0.855，颈围=0.204）和 FFMI（在生物电阻抗模型中；：0.891；：年龄=0.906，FFMI=0.199）是 AS 的显著横断面预测因子。当所有参数一起纳入时（人体测量学和生物电阻抗学参数均纳入），颈围和 FFMI 再次与 AS 显著相关（：0.894；：年龄=0.882，FFMI=0.126，颈围=0.093）。
总之，无论潜在混杂因素和其他人体测量学和生物电阻抗衍生参数如何，FFMI 和颈围与 AS 相关。
