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用于伤口愈合与感染控制的纳米材料

Nanomaterials for Wound Healing and Infection Control.

作者信息

Mihai Mara Madalina, Dima Monica Beatrice, Dima Bogdan, Holban Alina Maria

机构信息

Dermavenereology Department, Emergency University Hospital "Elias", 011461 Bucharest, Romania.

Department of Oncologic Dermatology-Emergency University Hospital "Elias", University of Medicine and Pharmacy "Carol Davila", 020021 Bucharest, Romania.

出版信息

Materials (Basel). 2019 Jul 6;12(13):2176. doi: 10.3390/ma12132176.

Abstract

Wound healing has been intensely studied in order to develop an "ideal" technique that achieves expeditious recovery and reduces scarring to the minimum, thus ensuring function preservation. The classic approach to wound management is represented by topical treatments, such as antibacterial or colloidal agents, in order to prevent infection and promote a proper wound-healing process. Nanotechnology studies submicroscopic particles (maximum diameter of 100 nm), as well as correlated phenomena. Metal nanoparticles (e.g., silver, gold, zinc) are increasingly being used in dermatology, due to their beneficial effect on accelerating wound healing, as well as treating and preventing bacterial infections. Other benefits include: ease of use, less frequent dressing changes and a constantly moist wound environment. This review highlights recent findings regarding nanoparticle application in wound management.

摘要

为了开发一种能实现快速恢复并将疤痕减少到最低限度从而确保功能保留的“理想”技术,伤口愈合已得到深入研究。伤口处理的经典方法是以局部治疗为代表,比如使用抗菌剂或胶体剂,以预防感染并促进适当的伤口愈合过程。纳米技术研究亚微观粒子(最大直径为100纳米)以及相关现象。金属纳米粒子(如银、金、锌)因其对加速伤口愈合以及治疗和预防细菌感染的有益作用,在皮肤科越来越多地被使用。其他优点包括:使用方便、换药频率较低以及伤口环境持续湿润。这篇综述重点介绍了纳米粒子在伤口处理应用方面的最新研究结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca5b/6650835/a3935330078c/materials-12-02176-g001.jpg

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