Department of Epidemiology and Population Health, The London School of Hygiene and Tropical Medicine , London , UK.
Department of Psychology, University of Essex , Colchester , UK.
Hum Vaccin Immunother. 2019;15(9):2081-2089. doi: 10.1080/21645515.2019.1638203. Epub 2019 Aug 23.
Pregnancy represents a high information need state, where uncertainty around medical intervention is common. As such, the pertussis vaccination given during pregnancy presents a unique opportunity to study the interaction between vaccine attitudes and vaccine information-seeking behavior. We surveyed a sample of pregnant women (N = 182) during early pregnancy and again during late pregnancy. The variables of vaccine confidence and risk perception of vaccination during pregnancy were measured across two questionnaires. Additional variables of decision conflict and intention to vaccinate were recorded during early pregnancy, while vaccine information-seeking behavior and vaccine uptake were recorded during late pregnancy. 88.8% of participants reported seeking additional information about the pertussis vaccine during pregnancy. Women that had a lower confidence in vaccination ( .004) and those that saw the risk of pertussis disease as high compared to the risk of side effects from the pertussis vaccination during pregnancy ( = .004) spent significantly more time seeking information about the pertussis vaccination. Women's perception of risk related to vaccination during pregnancy significantly changed throughout the pregnancy ((182) = 4.685 < .001), with women perceiving the risk of pertussis disease higher as compared to the risk of side effects from the vaccine as the pregnancy progresses. The strength and influence of information found through seeking was predicted by intention to vaccinate ( = .011). As such, we suggest that intention to vaccinate during early pregnancy plays a role in whether the information found through seeking influences women towards or away from vaccination.
妊娠是一个高信息量的状态,对医疗干预的不确定性很常见。因此,妊娠期间接种百日咳疫苗为研究疫苗态度和疫苗信息寻求行为之间的相互作用提供了一个独特的机会。我们在妊娠早期和晚期对一组孕妇(N=182)进行了调查。在两个问卷中测量了疫苗信心和妊娠期间接种疫苗的风险感知变量。在妊娠早期记录了决策冲突和接种意愿等额外变量,而在妊娠晚期记录了疫苗信息寻求行为和疫苗接种情况。88.8%的参与者报告在妊娠期间寻求有关百日咳疫苗的额外信息。对疫苗接种信心较低的女性(.004)和认为妊娠期间百日咳病的风险高于疫苗副作用风险的女性(.004)花费更多的时间来寻找有关百日咳疫苗的信息。女性对妊娠期间接种疫苗相关风险的感知在整个妊娠期间发生了显著变化((182)=4.685<.001),随着妊娠的进展,女性认为百日咳病的风险高于疫苗副作用的风险。通过寻求发现的信息的强度和影响力可由接种意愿预测( =.011)。因此,我们认为,妊娠早期的接种意愿在通过寻求发现的信息是否会影响女性接种疫苗方面起着作用。