Chinain M, Gatti C M, Roué M, Darius H T
Institut Louis Malardé, Laboratory of Marine Biotoxins-UMR 241-EIO, Papeete, Tahiti, French Polynesia.
Institut de Recherche pour le Développement-UMR 241-EIO, Pirae, Tahiti, French Polynesia.
New Microbes New Infect. 2019 Jun 7;31:100565. doi: 10.1016/j.nmni.2019.100565. eCollection 2019 Sep.
Ciguatera is a non-bacterial seafood poisoning highly prevalent in French Polynesia where it constitutes a major health issue and a major threat to food sustainability and food security for local populations. Ciguatera results from the bioaccumulation in marine food webs of toxins known as ciguatoxins, originating from benthic dinoflagellates in the genera and . Ciguatera is characterized by a complex array of gastrointestinal, neurological and cardiovascular symptoms. The effective management of patients is significantly hampered by the occurrence of atypical forms and/or chronic sequelae in some patients, and the lack of both a confirmatory diagnosis test and a specific antidote. In addition, recent findings have outlined the implication of novel species of the causative organisms as well as new vectors, namely marine invertebrates, in ciguatera outbreaks. Another novel trend relates to the geographical expansion of this disease to previously unaffected areas, not only in certain island groups of French Polynesia but also in temperate regions worldwide, as a likely consequence of the effects of climate change.
雪卡毒素中毒是一种非细菌性海鲜中毒，在法属波利尼西亚极为普遍，它构成了一个重大的健康问题，并且对当地居民的食物可持续性和食品安全构成重大威胁。雪卡毒素中毒是由雪卡毒素在海洋食物网中的生物累积引起的，雪卡毒素源自底栖甲藻纲的 和 属。雪卡毒素中毒的特征是一系列复杂的胃肠道、神经和心血管症状。在一些患者中出现非典型形式和/或慢性后遗症，以及缺乏确诊诊断测试和特效解毒剂，这严重阻碍了对患者的有效治疗。此外，最近的研究结果表明，致病生物的新物种以及新的载体，即海洋无脊椎动物，在雪卡毒素中毒事件中也有牵连。另一个新趋势是这种疾病在地理上扩展到以前未受影响的地区，这不仅发生在法属波利尼西亚的某些岛屿群，也发生在全球温带地区，这可能是气候变化影响的结果。
