Fanconi S, Sigrist H
Intensive Care Unit, University Children's Hospital, Zürich, Switzerland.
J Clin Monit. 1988 Apr;4(2):103-6. doi: 10.1007/BF01641810.
We evaluated a new combined sensor for monitoring transcutaneous carbon dioxide tension (PtcCO2) and oxygen tension (PtcO2) in 20 critically ill newborn infants. Arterial oxygen tension (PaO2) ranged from 16 to 126 torr and arterial carbon dioxide tension (PaCO2) from 14 to 72 torr. Linear correlation analysis (100 paired values) of PtcO2 versus PaO2 showed an r value of 0.75 with a regression equation of PtcO2 = 8.59 + 0.905 (PaO2), while PtcCO2 versus PaCO2 revealed a correlation coefficient of r = 0.89 with an equation of PtcCO2 = 2.53 + 1.06 (PaCO2). The bias between PaO2 and PtcO2 was -2.8 with a precision of +/- 16.0 torr (range, -87 to +48 torr). The bias between PaCO2 and PtcCO2 was -5.1 with a precision of +/- 7.3 torr (range, -34 to +8 torr). The transcutaneous sensor detected 83% of hypoxia (PaO2 less than 45 torr), 75% of hyperoxia (PaO2 greater than 90 torr), 45% of hypocapnia (PaCO2 less than 35 torr), and 96% of hypercapnia (PaCO2 greater than 45 torr). We conclude that the reliability of the combined transcutaneous PO2 and PCO2 monitor in sick neonates is good for detecting hypercapnia, fair for hypoxia and hyperoxia, but poor for hypocapnia. It is an improvement in that it spares available skin surface and requires less handling, but it appears to be slightly less accurate than the single electrodes.
我们对一种用于监测20例危重新生儿经皮二氧化碳分压（PtcCO2）和氧分压（PtcO2）的新型组合传感器进行了评估。动脉氧分压（PaO2）范围为16至126托，动脉二氧化碳分压（PaCO2）范围为14至72托。PtcO2与PaO2的线性相关分析（100对数值）显示r值为0.75，回归方程为PtcO2 = 8.59 + 0.905（PaO2），而PtcCO2与PaCO2的相关系数r = 0.89，方程为PtcCO2 = 2.53 + 1.06（PaCO2）。PaO2与PtcO2之间的偏差为-2.8，精度为±16.0托（范围为-87至+48托）。PaCO2与PtcCO2之间的偏差为-5.1，精度为±7.3托（范围为-34至+8托）。经皮传感器检测到83%的低氧血症（PaO2低于45托）、75%的高氧血症（PaO2高于90托）、45%的低碳酸血症（PaCO2低于35托）和96%的高碳酸血症（PaCO2高于45托）。我们得出结论，组合式经皮PO2和PCO2监测仪在患病新生儿中检测高碳酸血症的可靠性良好，检测低氧血症和高氧血症的可靠性一般，但检测低碳酸血症的可靠性较差。它的改进之处在于节省了可用的皮肤表面且操作较少，但似乎比单电极的准确性略低。
