Hazinski T A, Severinghaus J W
Med Instrum. 1982 May-Jun;16(3):150-3.
Commercially available skin surface PCO2 sensors, when properly maintained, calibrated, and applied, report arterial PCO2 over a wide range of values and in virtually all clinical conditions to an accuracy of +/- 3 torr. Inappropriate mathematical treatment of in vivo skin surface-arterial PCO2 comparisons has led to controversy regarding the precise relationship between these variables. The proper method of calibration involves applying a temperature correction factor of 4.5%/degrees C to the calibration gas setting, and subtracting 4 torr by offsetting zero. For analysis of accuracy, the resulting corrected values should be used to determine the mean and standard deviation of the skin surface:arterial PCO2 ratio. Tests of correlation as a function of PaCO2 require deliberate wide variation of PCO2 within each subject of a test group. Skin surface PCO2 monitors record blood gas tensions continuously and noninvasively, and they can be used to study cardiorespiratory function in normal subjects, in whom arterial blood sampling would be difficult to justify--two distinct advantages of the devices.
市售的皮肤表面二氧化碳分压（PCO2）传感器，在经过适当维护、校准和应用后，能在广泛的数值范围内，且几乎在所有临床情况下，以±3托的精度报告动脉血PCO2。对体内皮肤表面与动脉血PCO2比较进行不恰当的数学处理，引发了关于这些变量之间精确关系的争议。正确的校准方法包括在校准气体设置上应用4.5%/℃的温度校正因子，并通过调零减去4托。为分析准确性，应使用所得的校正值来确定皮肤表面与动脉血PCO2比值的均值和标准差。作为动脉血二氧化碳分压（PaCO2）函数的相关性测试，需要在测试组的每个受试者内故意使PCO2有较大范围的变化。皮肤表面PCO2监测仪能连续、无创地记录血气张力，可用于研究正常受试者的心肺功能，在这类受试者中进行动脉血采样很难说得过去——这是该设备的两个明显优势。
