Arora Suraj, Das Gotam, Alqarni Mohammed, Grover Vishakha, Manzoor Baba Suheel, Saluja Priyanka, Hassan Saeed Awod Bin, Abdulla Anshad M, Bavabeedu Shashit Shetty, Abullais Shahabe Saquib, Chahal Gurparkash Singh, Ohri Anchal
Department of Restorative Dental Sciences, College of Dentistry, King Khalid University, Abha 61321, Saudi Arabia.
Department of Prosthodontics, College of Dentistry, King Khalid University, Abha 61421, Saudi Arabia.
Gels. 2023 Aug 29;9(9):698. doi: 10.3390/gels9090698.
Biopolymers are organic polymers that can be treated into intricate designs with porous characteristics that mimic essential biologic components. Due to their superior biosafety, biodegradability, biocompatibility, etc., they have been utilized immensely in biomedical engineering, regeneration, and drug delivery. To obtain the greatest number of results, a literature search was undertaken in scientific search engines utilizing keywords. Chitosan is used in a variety of medical sectors, with the goal of emphasizing its applications and benefits in the clinical dental industry. Chitosan can be dissolved in liquid form and combined with other substances to create a variety of products, including fibers, hydrogels, membranes, microspheres, resins, sponges, pastes, tablets, and micro granules. Chitosan has been studied in a variety of dental applications. Chitosan is used in the prevention of caries and wear, in pulpotomy to accelerate osteogenesis in guided tissue regeneration due to its hemostatic property, and primarily to benefit from its antimicrobial activity by adding it to materials, such as glass ionomer cement, calcium hydroxide, and adhesive systems. With its antibacterial activity and biocompatibility, chitosan is leading the pack as a promising ingredient in the production of dental materials. The current review provides an update on the background, fundamentals, and wide range of uses of chitosan and its gels in dental science.
生物聚合物是有机聚合物，可被加工成具有模仿基本生物成分的多孔特性的复杂设计。由于其卓越的生物安全性、生物降解性、生物相容性等，它们在生物医学工程、再生和药物递送中得到了广泛应用。为了获得最多的结果，利用关键词在科学搜索引擎中进行了文献检索。壳聚糖被用于多个医学领域，目的是强调其在临床牙科行业中的应用和益处。壳聚糖可以以液体形式溶解，并与其他物质结合以制造各种产品，包括纤维、水凝胶、膜、微球、树脂、海绵、糊剂、片剂和微粒。壳聚糖已在多种牙科应用中得到研究。壳聚糖用于预防龋齿和磨损，在牙髓切断术中因其止血特性可加速引导组织再生中的骨生成，并且主要是通过将其添加到诸如玻璃离子粘固剂、氢氧化钙和粘结系统等材料中来受益于其抗菌活性。凭借其抗菌活性和生物相容性，壳聚糖作为牙科材料生产中有前景的成分处于领先地位。本综述提供了关于壳聚糖及其凝胶在牙科科学中的背景、基本原理和广泛用途的最新信息。
