MMWR Morb Mortal Wkly Rep. 2019 Jul 26;68(29):642-646. doi: 10.15585/mmwr.mm6829a3.
The number of wild poliovirus (WPV) cases in Nigeria decreased from 1,122 in 2006 to six WPV type 1 (WPV1) in 2014 (1). During August 2014-July 2016, no WPV cases were detected; during August-September 2016, four cases were reported in Borno State. An insurgency in northeastern Nigeria had resulted in 468,800 children aged <5 years deprived of health services in Borno by 2016. Military activities in mid-2016 freed isolated families to travel to camps, where the four WPV1 cases were detected. Oral poliovirus vaccine (OPV) campaigns were intensified during August 2016-December 2017; since October 2016, no WPV has been detected (2). Vaccination activities in insurgent-held areas are conducted by security forces; however, 60,000 unvaccinated children remain in unreached settlements. Since 2018, circulating vaccine-derived poliovirus type 2 (cVDPV2) has emerged and spread from Nigeria to Niger and Cameroon; outbreak responses to date have not interrupted transmission. This report describes progress in Nigeria polio eradication activities during January 2018-May 2019 and updates the previous report (2). Interruption of cVDPV2 transmission in Nigeria will need increased efforts to improve campaign quality and include insurgent-held areas. Progress in surveillance and immunization activities will continue to be reviewed, potentially allowing certification of interruption of WPV transmission in Africa in 2020.
尼日利亚的野生脊髓灰质炎病毒(WPV)病例数量从 2006 年的 1122 例下降到 2014 年的 6 例 WPV1 型(1)。2014 年 8 月至 2016 年 7 月期间未发现 WPV 病例;2016 年 8 月至 9 月,在博尔诺州报告了 4 例病例。尼日利亚东北部的叛乱导致 2016 年博尔诺州有 46.88 万名 5 岁以下儿童无法获得卫生服务。2016 年中期的军事活动使孤立的家庭得以前往营地,在那里发现了 4 例 WPV1 型病例。2016 年 8 月至 2017 年 12 月期间加强了口服脊髓灰质炎疫苗(OPV)运动;自 2016 年 10 月以来,未再发现 WPV(2)。叛乱地区的免疫接种活动由安全部队进行;然而,仍有 6 万名儿童未接种疫苗,居住在尚未覆盖的定居点。自 2018 年以来,循环疫苗衍生脊髓灰质炎病毒 2 型(cVDPV2)已从尼日利亚传播至尼日尔和喀麦隆;迄今为止的疫情应对措施并未中断传播。本报告介绍了 2018 年 1 月至 2019 年 5 月期间尼日利亚脊髓灰质炎根除活动的进展情况,并更新了前一份报告(2)。要想阻断尼日利亚 cVDPV2 的传播,就需要加大努力,提高运动质量,并将叛乱地区包括在内。将继续审查监测和免疫活动的进展情况,这有可能使 2020 年在非洲认证 WPV 传播的中断。