Hećimović Ana, Heaney Alice, McKenna Stephen P, Basara Latinka, Jakopović Marko, Vukić Dugac Andrea, Redžepi Gzim, Rotim Cecilija, Samaržija Miroslav, Jokić-Begić Nataša, Popović-Grle Sanja
1Department for Lung Diseases, Zagreb University Hospital Centre, Zagreb, Croatia; 2Galen Research, Manchester, UK; 3School of Medicine, University of Zagreb, Zagreb, Croatia; 4Dr. Andrija Štampar Teaching Institute of Public Health, Zagreb, Croatia; 5Faculty of Humanities and Social Science, University of Zagreb, Zagreb, Croatia.
Acta Clin Croat. 2019 Mar;58(1):3-12. doi: 10.20471/acc.2019.58.01.01.
Pulmonary hypertension (PH) is a chronic disease which severely impairs quality of life (QoL). The Cambridge Pulmonary Hypertension Outcome Review (CAMPHOR) is the first disease-specific tool to assess patient-reported symptoms, functioning and QoL in PH patients. The aim of this study was to adapt and validate the CAMPHOR for use in Croatia. The adaptation process involved three stages: translation (bilingual and lay panel), cognitive debriefing interviews with patients and psychometric validation. For the latter stage, a postal survey was conducted with 50 patients to examine the reliability and validity of the adapted scale. All three scales of the Croatian CAMPHOR demonstrated excellent internal consistency (Symptoms = 0.93; Activity limitations = 0.94; QoL = 0.92) and test-retest reliability correlations (Symptoms = 0.90; Activity limitations = 0.95; QoL = 0.90). Predicted correlations with the SF-36 scales provided evidence for construct validity of the CAMPHOR scales. Evidence for known group validity was shown by the ability of the scales to distinguish between participants based on patient-perceived general health and disease severity. The Croatian version of the CAMPHOR is a valid and reliable tool for use in clinical routine and clinical research.
肺动脉高压（PH）是一种严重损害生活质量（QoL）的慢性疾病。剑桥肺动脉高压结局评估（CAMPHOR）是首个用于评估肺动脉高压患者自我报告的症状、功能和生活质量的疾病特异性工具。本研究的目的是对CAMPHOR进行改编并验证其在克罗地亚的适用性。改编过程包括三个阶段：翻译（双语和外行小组）、对患者进行认知反馈访谈以及心理测量学验证。对于后一阶段，对50名患者进行了邮寄调查，以检验改编后量表的信度和效度。克罗地亚版CAMPHOR的所有三个量表均显示出出色的内部一致性（症状=0.93；活动受限=0.94；生活质量=0.92）和重测信度相关性（症状=0.90；活动受限=0.95；生活质量=0.90）。与SF-36量表的预测相关性为CAMPHOR量表的结构效度提供了证据。量表能够根据患者自我感知的总体健康状况和疾病严重程度区分参与者，这表明了已知群体效度。克罗地亚版CAMPHOR是一种在临床常规和临床研究中使用的有效且可靠的工具。
