非典型 ST2- 和 CD127- 阴性肺 ILC2 群体是由真菌过敏原链格孢诱导产生的。
Unconventional ST2- and CD127-negative lung ILC2 populations are induced by the fungal allergen Alternaria alternata.
机构信息
Department of Medicine, University of California, San Diego, Calif.
La Jolla Institute for Allergy and Immunology, La Jolla, Calif.
出版信息
J Allergy Clin Immunol. 2019 Nov;144(5):1432-1435.e9. doi: 10.1016/j.jaci.2019.07.018. Epub 2019 Jul 29.
Abstract
We demonstrate that unconventional ST2- and CD127-negative ILC2 populations are present in mouse lung and are induced by , suggesting commonly used ILC2 identification practices do not accurately enumerate the total burden of type 2 cytokine producing ILC2s.
摘要
我们证明了非常规的 ST2- 和 CD127- 阴性 ILC2 群体存在于小鼠肺部，并由 诱导，这表明常用的 ILC2 鉴定方法不能准确地计数 2 型细胞因子产生 ILC2 的总负担。
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