Department of Health Sciences, University "Magna Graecia", Viale Europa-Germaneto, 88110 Catanzaro, Italy.
Greenwood Genetic Center, 113 Gregor Mendel Circle, Greenwood, SC 29646, USA.
Int J Environ Res Public Health. 2019 Aug 21;16(17):3011. doi: 10.3390/ijerph16173011.
Lifestyle interventions remain the first-line treatment for non-alcoholic fatty liver disease (NAFLD), even if the optimal alimentary regimen is still controversial. The interest in antioxidants has increased over time, and literature reports an inverse association between nutrients rich in antioxidants and the risk of mortality due to non-communicable diseases, including NAFLD. Mediterranean diet (MD) is a model characterized by main consumption of plant-based foods and fish and reduced consumption of meat and dairy products. MD represents the gold standard in preventive medicine, probably due to the harmonic combination of many foods with antioxidant and anti-inflammatory properties. This regimen contributes substantially to the reduction of the onset of many chronic diseases as cardiovascular diseases, hypertension, type 2 diabetes mellitus, obesity, cancer, and NAFLD. The present review aims to clarify the intake of antioxidants typical of the MD and evaluate their effect on NAFLD.
生活方式干预仍然是非酒精性脂肪性肝病 (NAFLD) 的一线治疗方法，即使最佳饮食方案仍存在争议。抗氧化剂的研究兴趣日益增加，文献报道富含抗氧化剂的营养素与非传染性疾病（包括 NAFLD）导致的死亡率呈负相关。地中海饮食 (MD) 是一种以植物性食物和鱼类为主，减少肉类和奶制品摄入的模式。MD 是预防医学的金标准，可能是由于许多具有抗氧化和抗炎特性的食物的和谐组合。这种饮食方案在减少许多慢性疾病的发生方面发挥了重要作用，如心血管疾病、高血压、2 型糖尿病、肥胖症、癌症和 NAFLD。本综述旨在阐明 MD 中典型的抗氧化剂的摄入量，并评估其对 NAFLD 的影响。
