Department of Orthopaedic Surgery, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano, 390-8621, Japan.
Rehabilitation Center, Shinshu University Hospital, 3-1-1 Asahi, Matsumoto, Nagano, 390-8621, Japan.
Sci Rep. 2019 Aug 22;9(1):12242. doi: 10.1038/s41598-019-48793-y.
This report searched for relationships between physical performance and other health indices through a detailed investigation of a randomly sampled cohort from a basic town resident registry. Residents between the age of 50 and 89 years were randomly sampled from the basic resident registry of a cooperating town for construction of a 415-participant cohort that minimized selection bias. Cognitive function measures, annual fall frequency, and SF-8 as an HRQOL measure were the outcomes of interest. The impact of physical function on outcomes was predicted using multivariate regression models with age and gender as covariates. Knee muscle strength, grip strength, one-leg standing time, and two-step test score had a significant impact on cognitive scores and SF-8 physical component summary scores. A shift of -1 standard deviation for grip strength, the stand-up test, and the two-step test increased fall risk by 39%, 23%, and 38%, respectively. In conclusion, diminished physical performance is related to serious problems in older individuals, specifically cognitive deterioration, increased fall risk, and inability to maintain HRQOL. These factors are independent of age and gender. Thus, the higher physical function can be maintained in older people, the better the other conditions appear to remain.
本报告通过对合作城镇基本居民登记处的随机抽样队列进行详细调查,寻找身体机能与其他健康指标之间的关系。从合作城镇的基本居民登记处随机抽取年龄在 50 至 89 岁之间的居民,以最小化选择偏差的方式构建了一个由 415 名参与者组成的队列。认知功能测量、每年跌倒频率以及作为 HRQOL 测量的 SF-8 是感兴趣的结果。使用多元回归模型,以年龄和性别为协变量,预测身体功能对结果的影响。膝关节肌肉力量、握力、单腿站立时间和两步测试评分对认知评分和 SF-8 生理成分综合评分有显著影响。握力、站立测试和两步测试的标准偏差降低一个单位,跌倒风险分别增加 39%、23%和 38%。总之,身体机能下降与老年人的严重问题有关,特别是认知能力下降、跌倒风险增加和无法维持 HRQOL。这些因素与年龄和性别无关。因此,老年人保持较高的身体机能,其他状况似乎保持得越好。