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叶提取物对从单峰骆驼脓肿中分离出的化脓性细菌的抗菌功效。

Antibacterial efficacy of leaf extract against pyogenic bacteria isolated from a dromedary camel () abscess.

作者信息

Fouad Ehab Ali, Abu Elnaga Azza S M, Kandil Mai M

机构信息

Department of Microbiology and Immunology, National Research Centre, Egypt.

出版信息

Vet World. 2019 Jun;12(6):802-808. doi: 10.14202/vetworld.2019.802-808. Epub 2019 Jun 14.

DOI:10.14202/vetworld.2019.802-808
PMID:31439997
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6661477/
Abstract

BACKGROUND

Abscess in camel is one of the most important bacterial infections. It causes anemia and emaciation, resulting in an economic loss due to carcass condemnation and a decrease in reproductive and production efficiency.

AIM

This investigation aimed to isolate the bacteria from abscesses in camels and evaluate the antibacterial activity of extracts.

MATERIALS AND METHODS

Disk diffusion method and minimum inhibitory concentration were used for the evaluation of the antibacterial activity of extracts against isolated bacteria from camel abscesses.

RESULTS

The isolated bacteria were displayed relatively as follows: (30.4%), (25.8%), (17.8%), (10.5%), (8.5%), (8.5%), spp. (6.7%), (5.2%), spp. (4.2%), and (1.7%). The drugs of choice for isolates were ciprofloxacin and trimethoprim/sulfamethoxazole, whereas amikacin, ciprofloxacin, gentamicin, neomycin, novobiocin, streptomycin, and vancomycin were for s isolates. Moreover, the ethanol extracts of showed higher antibacterial efficacy than the cold aqueous extracts.

CONCLUSION

is considered one of the new infection-fighting strategies in controlling pyogenic bacteria responsible for camel abscesses.

摘要

背景

骆驼脓肿是最重要的细菌感染之一。它会导致贫血和消瘦,因胴体被判不合格以及繁殖和生产效率下降而造成经济损失。

目的

本研究旨在从骆驼脓肿中分离细菌,并评估提取物的抗菌活性。

材料与方法

采用纸片扩散法和最低抑菌浓度法评估提取物对从骆驼脓肿中分离出的细菌的抗菌活性。

结果

分离出的细菌相对比例如下:金黄色葡萄球菌(30.4%)、化脓隐秘杆菌(25.8%)、无乳链球菌(17.8%)、停乳链球菌(10.5%)、乳房链球菌(8.5%)、金黄色微球菌(8.5%)、芽孢杆菌属(6.7%)、表皮葡萄球菌(5.2%)、棒杆菌属(4.2%)和溶血葡萄球菌(1.7%)。针对金黄色葡萄球菌分离株的首选药物是环丙沙星和甲氧苄啶/磺胺甲恶唑,而针对停乳链球菌分离株的药物是阿米卡星、环丙沙星、庆大霉素、新霉素、新生霉素、链霉素和万古霉素。此外,地锦草的乙醇提取物比冷浸水溶液提取物显示出更高的抗菌效果。

结论

地锦草被认为是控制导致骆驼脓肿的化脓性细菌的新抗感染策略之一。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1423/6661477/e7e69b550d32/Vetworld-12-802-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1423/6661477/e7e69b550d32/Vetworld-12-802-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1423/6661477/e7e69b550d32/Vetworld-12-802-g001.jpg

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