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尸检时可能遇到的结核病特征性表现图谱概述。

An atlas overview of characteristic features of tuberculosis that may be encountered at autopsy.

机构信息

Forensic Science South Australia (FSSA) and the School of Medicine, The University of Adelaide, Level 2 Medical School North Building, Frome Road, Adelaide, South Australia, 5000, Australia.

出版信息

Forensic Sci Med Pathol. 2020 Mar;16(1):143-151. doi: 10.1007/s12024-019-00161-y. Epub 2019 Aug 30.

DOI:10.1007/s12024-019-00161-y
PMID:31471869
Abstract

Tuberculosis (TB) is a bacterial infection caused by Mycobacterium tuberculosis. Although primarily a disease of the respiratory system it may be found in any organ or tissue. Global population movements and the emergence of resistant strains are contributing to increasing numbers of cases in certain populations. Subtlety of symptoms and signs, chronicity of disease and failure to seek medical assistance may result in the diagnosis only being made at the time of autopsy. For this reason forensic pathologists need to understand the protean manifestations of the disease and the variable mechanisms by which TB may cause death. This atlas overview provides descriptions of the pathological manifestations of TB in a variety of organs with accompanying illustrations. It serves as a summary of conditions that should be checked for at autopsy in suspected or confirmed cases.

摘要

肺结核(TB)是由结核分枝杆菌引起的细菌性感染。虽然它主要是一种呼吸系统疾病,但它也可能发生在任何器官或组织中。全球人口流动和耐药菌株的出现导致某些人群中的病例数量不断增加。症状和体征不明显、疾病慢性化以及未能寻求医疗帮助,可能导致只有在尸检时才做出诊断。因此,法医病理学家需要了解这种疾病的多形性表现以及 TB 导致死亡的各种机制。本图谱概述提供了各种器官中 TB 的病理表现描述,并附有插图。它是疑似或确诊病例尸检时应检查的条件摘要。

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Case Rep Med. 2018 Feb 25;2018:6068258. doi: 10.1155/2018/6068258. eCollection 2018.
2
Tuberculosis epididymitis complicated by a cutaneous fistula.结核性附睾炎并发皮肤瘘管。
BMJ Case Rep. 2017 Nov 9;2017:bcr-2017-221346. doi: 10.1136/bcr-2017-221346.
3
Massive hemoptysis from Rasmussen's aneurysm in active pulmonary tuberculosis; A case report of successful treatment with bronchial artery embolization.
Cureus. 2023 Oct 25;15(10):e47635. doi: 10.7759/cureus.47635. eCollection 2023 Oct.
4
Role of MHC class I pathways in antigen presentation.MHC Ⅰ类途径在抗原呈递中的作用。
Front Cell Infect Microbiol. 2023 Mar 15;13:1107884. doi: 10.3389/fcimb.2023.1107884. eCollection 2023.
活动性肺结核患者拉斯姆森动脉瘤所致大量咯血;支气管动脉栓塞术成功治疗1例报告
Respir Med Case Rep. 2017 Oct 20;22:277-279. doi: 10.1016/j.rmcr.2017.10.003. eCollection 2017.
4
Acute myocarditis secondary to cardiac tuberculosis: a case report.心脏结核继发急性心肌炎:一例报告
Echo Res Pract. 2017 Sep;4(3):K25-K29. doi: 10.1530/ERP-17-0024. Epub 2017 Aug 16.
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Peritoneal tuberculosis as a cause of ascites in a patient with cirrhosis.腹膜结核作为肝硬化患者腹水的一个病因。
BMJ Case Rep. 2017 Jul 14;2017:bcr-2017-220500. doi: 10.1136/bcr-2017-220500.
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Identifying mechanisms driving formation of granuloma-associated fibrosis during Mycobacterium tuberculosis infection.确定结核分枝杆菌感染期间驱动肉芽肿相关纤维化形成的机制。
J Theor Biol. 2017 Sep 21;429:1-17. doi: 10.1016/j.jtbi.2017.06.017. Epub 2017 Jun 20.
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Microbiol Spectr. 2017 Jan;5(1). doi: 10.1128/microbiolspec.TNMI7-0015-2016.
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