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美国特殊需求人群中的口腔人乳头瘤病毒(HPV)患病率及HPV疫苗接种情况

Oral HPV prevalence and HPV vaccination among special needs population in the US.

作者信息

Chandrupatla Siddardha G, Khalid Isma, Tavares Mary

机构信息

Part-time Faculty, Dept. of Oral Health Policy and Epidemiology, Harvard School of Dental Medicine, USA.

Resident, Pediatric Dentistry, Henry M. Goldman School of Dental Medicine, Boston University, USA.

出版信息

Papillomavirus Res. 2019 Dec;8:100182. doi: 10.1016/j.pvr.2019.100182. Epub 2019 Aug 29.

Abstract

INTRODUCTION

Special needs population have barriers accessing healthcare, higher incidence of sexual assaults and lower sexual education. Due to the above this study was conducted- 1) To assess the current prevalence of oral HPV infection among individuals with SHCN (special health care needs) as compared to the general population and 2) To compare the prevalence of HPV vaccination in SHCN individuals (within the recommended age groups) to general population.

METHODS

This data was obtained from NHANES 2013-14 and included 665 individuals with special needs. Weighted prevalence estimates and prevalence ratios (PR) were calculated for oral HPV infection by gender, age (18-59 years), race, smoking history, economic status, and sexual behavior. Prevalence rates were calculated for HPV vaccination.

RESULTS

Oral HPV was detected in 9% (7.1-11.5; p = 0.05) of special needs adults. High-risk HPV genotypes prevalence was also higher among adults with special needs [5.56% (3.9-7.9) vs 3.87% (2.7-5.4)]. The HPV vaccination rates among 9-26 years special needs females (33.5% vs 37%) and males aged 9-21 years (16.7% vs 21.2%) with special needs was lower than non-special needs individuals.

CONCLUSION

There is higher burden of oral HPV infection among adults with special needs compared to general population. Contrastingly, lower vaccination rates were observed among them within the recommended age groups. Further studies are required to determine the barriers to HPV vaccination among individuals with special needs.

摘要

引言

特殊需求人群在获得医疗保健方面存在障碍,遭受性侵犯的发生率较高,性教育水平较低。基于上述情况开展了本研究:1)评估有特殊医疗需求(SHCN)的个体中口腔人乳头瘤病毒(HPV)感染的当前患病率,并与普通人群进行比较;2)比较SHCN个体(在推荐年龄组内)与普通人群的HPV疫苗接种率。

方法

该数据来自2013 - 2014年美国国家健康与营养检查调查(NHANES),包括665名有特殊需求的个体。按性别、年龄(18 - 59岁)、种族、吸烟史、经济状况和性行为计算口腔HPV感染的加权患病率估计值和患病率比(PR)。计算HPV疫苗接种的患病率。

结果

在9%(7.1 - 11.5;p = 0.05)的有特殊需求的成年人中检测到口腔HPV。有特殊需求的成年人中高危HPV基因型的患病率也更高[5.56%(3.

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