Myndrul Valerii, Iatsunskyi Igor
NanoBioMedical Centre, Adam Mickiewicz University, 3, Wszechnicy Piastowskiej Str., 61-614 Poznan, Poland.
Materials (Basel). 2019 Sep 6;12(18):2880. doi: 10.3390/ma12182880.
This review highlights the application of different types of nanosilicon (nano-Si) materials and nano-Si-based composites for (bio)sensing applications. Different detection approaches and (bio)functionalization protocols were found for certain types of transducers suitable for the detection of biological compounds and gas molecules. The importance of the immobilization process that is responsible for biosensor performance (biomolecule adsorption, surface properties, surface functionalization, etc.) along with the interaction mechanism between biomolecules and nano-Si are disclosed. Current trends in the fabrication of nano-Si-based composites, basic gas detection mechanisms, and the advantages of nano-Si/metal nanoparticles for surface enhanced Raman spectroscopy (SERS)-based detection are proposed.
本综述重点介绍了不同类型的纳米硅（nano-Si）材料及纳米硅基复合材料在（生物）传感应用中的应用。针对某些适用于检测生物化合物和气体分子的换能器，发现了不同的检测方法和（生物）功能化方案。揭示了负责生物传感器性能的固定化过程（生物分子吸附、表面性质、表面功能化等）的重要性以及生物分子与纳米硅之间的相互作用机制。提出了纳米硅基复合材料制造的当前趋势、基本气体检测机制以及纳米硅/金属纳米颗粒用于基于表面增强拉曼光谱（SERS）检测的优势。
