School of Computing Science, University of Glasgow, Glasgow, Scotland, United Kingdom.
School of Mathematics and Statistics, University of Glasgow, Glasgow, Scotland, United Kingdom.
PLoS One. 2019 Sep 18;14(9):e0221869. doi: 10.1371/journal.pone.0221869. eCollection 2019.
Measurement of health-related quality of life (HRQL) is becoming increasingly valuable within veterinary preventative health care and chronic disease management, as well as in outcomes research. Initial reliability and validation of a 22 item shortened version of VetMetrica (VM), structured questionnaire instrument to measure HRQL in dogs via a mobile application was reported previously. Meaningful interpretation and presentation of the 4 domain scores comprising the HRQL profile generated by VM is key to its successful use in clinical practice and research. Study one describes transformation of domain scores from 0-6 to 0-100 and normalisation of these based on the healthy canine population in two age ranges, such that a score of 50 on a 0-100 scale represents the score for the age-related average healthy dog, and establishment of a threshold to assess domain-specific health status for individual dogs. This provides the clinician with a simple method of ascertaining the health status of an individual dog relative to the average healthy population in the same age group (norm-based scoring). Study two determines the minimum important difference (MID) in domain scores which represents the smallest improvement in score that is meaningful to the dog owner, thus providing the clinician with a means of recognising what is likely to be a significant improvement in scores for an individual dog over time. Visual representation of these guidelines for the purpose of interpreting VM profile scores is presented using case studies.
健康相关生活质量(HRQL)的测量在兽医预防保健和慢性病管理以及结果研究中变得越来越有价值。先前已经报道了一种名为 VetMetrica(VM)的 22 项简化版结构问卷工具,用于通过移动应用程序测量犬的 HRQL,该工具具有初始可靠性和有效性。VM 生成的 HRQL 特征的 4 个领域得分的有意义的解释和呈现是其在临床实践和研究中成功应用的关键。研究一描述了如何将域得分从 0-6 转换为 0-100,并基于两个年龄范围内的健康犬群对其进行归一化,使得 0-100 量表上的 50 分代表与年龄相关的平均健康犬的得分,以及为个体犬建立评估特定领域健康状况的阈值。这为临床医生提供了一种简单的方法来确定个体犬相对于同一年龄组中平均健康犬群的健康状况(基于标准的评分)。研究二确定了域得分的最小重要差异(MID),这代表了对犬主人有意义的得分最小改善,从而为临床医生提供了一种识别个体犬随时间得分可能显著改善的方法。使用案例研究展示了这些用于解释 VM 概况评分的指南的直观表示。