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高流量鼻治疗期间病原体传播潜力的评估。

Assessment of the potential for pathogen dispersal during high-flow nasal therapy.

机构信息

Department of Anesthesiology, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan; Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, USA.

Department of Anesthesiology, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan.

出版信息

J Hosp Infect. 2020 Apr;104(4):534-537. doi: 10.1016/j.jhin.2019.11.010. Epub 2019 Nov 20.

DOI:10.1016/j.jhin.2019.11.010
PMID:31759093
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7114853/
Abstract

High-flow nasal therapy is increasingly used in hospitals because of its effectiveness and patient comfort. However, pathogens in the patient's nasal and oral cavities may be dispersed by forced air. This study aimed to investigate the risk of pathogen dispersal during high-flow nasal therapy. Liquid and bacterial dispersal were assessed via in-vitro experimental set-ups using a manikin. Thickened water or fresh yeast solution mimicked saliva and nasal mucus secretions. Dispersal was limited to the proximal area of the face and nasal cannula, suggesting that high-flow nasal therapy does not increase the risk of droplet and contact infection.

摘要

高流量鼻氧疗法因其有效性和患者舒适度而在医院中得到越来越多的应用。然而,患者鼻腔和口腔中的病原体可能会被强制空气吹散。本研究旨在探讨高流量鼻氧疗法过程中病原体传播的风险。通过使用人工模型的体外实验装置评估了液体和细菌的扩散情况。增稠水或新鲜酵母溶液模拟唾液和鼻腔粘液分泌物。扩散仅限于面部和鼻氧管的近端区域,这表明高流量鼻氧疗法不会增加飞沫和接触感染的风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4145/7114853/0b2c417b06ee/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4145/7114853/c72b012dc8a2/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4145/7114853/0b2c417b06ee/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4145/7114853/c72b012dc8a2/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4145/7114853/0b2c417b06ee/gr2_lrg.jpg

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1
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Eur Respir Rev. 2017 Aug 9;26(145). doi: 10.1183/16000617.0028-2017. Print 2017 Sep 30.
2
Evaluation of the potential for virus dispersal during hand drying: a comparison of three methods.手部干燥过程中病毒传播潜力的评估:三种方法的比较
J Appl Microbiol. 2016 Feb;120(2):478-86. doi: 10.1111/jam.13014.
3
Facemasks for the prevention of infection in healthcare and community settings.医用口罩和普通口罩在预防医疗机构和社区感染中的作用
Current SARS-CoV-2 Protective Strategies for Healthcare Professionals.
医护人员当前针对严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的防护策略。
Biomedicines. 2023 Mar 7;11(3):808. doi: 10.3390/biomedicines11030808.
4
Characterization of SARS-CoV-2 Aerosols Dispersed During Noninvasive Respiratory Support of Patients With COVID-19.SARS-CoV-2 气溶胶在 COVID-19 患者无创性呼吸支持期间的分散特性。
Respir Care. 2023 Jan;68(1):8-17. doi: 10.4187/respcare.10340.
5
Bacterial Resistance to Antibiotics and Clonal Spread in COVID-19-Positive Patients on a Tertiary Hospital Intensive Care Unit, Czech Republic.捷克共和国一家三级医院重症监护病房中新冠病毒检测呈阳性患者的细菌对抗生素的耐药性及克隆传播情况
Antibiotics (Basel). 2022 Jun 8;11(6):783. doi: 10.3390/antibiotics11060783.
6
The Role of Noninvasive Respiratory Management in Patients with Severe COVID-19 Pneumonia.无创呼吸管理在重症新型冠状病毒肺炎患者中的作用
J Pers Med. 2021 Sep 3;11(9):884. doi: 10.3390/jpm11090884.
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BMJ. 2015 Apr 9;350:h694. doi: 10.1136/bmj.h694.
4
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5
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J Hosp Infect. 2015 Mar;89(3):215-7. doi: 10.1016/j.jhin.2014.11.007. Epub 2014 Dec 17.
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8
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9
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