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后路单开门椎管扩大成形钛板固定与锚钉固定的对比研究:临床疗效与颈椎矢状位平衡比较

Posterior open-door laminoplasty secured with titanium miniplates vs anchors: a comparative study of clinical efficacy and cervical sagittal balance.

机构信息

Orthopaedic Department, Chaoyang Hospital Affiliated to Capital Medical University, Beijing, 100020, China.

出版信息

J Orthop Surg Res. 2019 Nov 28;14(1):401. doi: 10.1186/s13018-019-1454-9.

Abstract

OBJECTIVE

Posterior open-door laminoplasty (PODL) is a common procedure for treating multilevel cervical spondylotic myelopathy (MCSM). Little information is available regarding the cervical sagittal balance and surgical efficacy of PODL when securing with different methods. Therefore, this study aims to investigate the clinical outcomes and the changes in cervical sagittal parameters and balance associated with PODL secured with titanium miniplates vs anchors.

METHOD

A retrospective analysis was performed on the clinical data of 79 patients with MCSM who were treated in our institution from January 2015 to December 2016. Among them, 42 patients were treated by PODL secured with titanium miniplates (group A) and 37 patients by PODL secured with anchors (group B). Surgical time, intraoperative blood loss, hospital stay, hospitalized cost, VAS scores of neck pain, JOA scores, neck disability index (NDI), and improvement rate of spinal neurological function (IRNF) were recorded before surgery and at 12 months after surgery. Before surgery, at 1 month and 2 years after surgery, the following radiological parameters were recorded and compared on the lateral cervical X-ray images: the distance from the vertical axis of C2 sagittal plane to the posterior superior edge of C7 (C2-7 SVA), the inclusion angle of tangent between C2 and C7 trailing edge (C2-7 Cobb angle), and the intersection angle between the upper edge of T1 and the horizontal line (T1 Slope).

RESULT

Comparing the two groups, there were no significant differences in surgical time, intraoperative blood loss, hospital stay, VAS, JOA, and NDI scores before surgery (P > 0.05); however, the hospitalized cost of group A were much higher than those of the group B (P < 0.05). At 2 years after surgery in the two groups, there was a significant reduction in VAS and NDI scores (P < 0.05), and JOA scores increased significantly (P < 0.05). In addition, there were no significant differences in VAS, JOA and IRNF between the two groups (P > 0.05); however, NDI scores of group A were better than those of group B (P < 0.05). In radiological parameters, before surgery, the two groups showed no significant differences in C2-7 SVA, C2-7 Cobb angle, and T1 slope (P > 0.05); however, after surgery, C2-7 SVA and T1 slope increased (P < 0.05), while C2-7 Cobb angle decreased (P < 0.05). At 2 years after surgery, the two groups did not differ significantly in C2-7 Cobb angle and T1 slope (P > 0.05), while C2-7 SVA of group A was superior to that of group B (P < 0.05). The difference value of C2-7 SVA measured before and after surgery was correlated negatively with that of NDI scores (P < 0.05).

CONCLUSION

PODL secured with titanium miniplates or anchors achieved good clinical efficacy in the treatment of MCSM. However, the patients with miniplates feel a better cervical functional status, while those with anchors spend less on hospitalization. Both methods lead to anteversion of cervical spine, but cervical sagittal balance after miniplates is better than that of anchors.

摘要

目的

后路单开门椎管扩大成形术(PODL)是治疗多节段脊髓型颈椎病(MCSM)的常用方法。关于使用不同方法固定后路单开门椎管扩大成形术时颈椎矢状位平衡和手术效果的信息较少。因此,本研究旨在探讨钛板与锚固定后路单开门椎管扩大成形术的临床疗效及与颈椎矢状参数和平衡相关的变化。

方法

回顾性分析 2015 年 1 月至 2016 年 12 月我院收治的 79 例 MCSM 患者的临床资料,其中 42 例行钛板固定后路单开门椎管扩大成形术(A 组),37 例行锚固定后路单开门椎管扩大成形术(B 组)。记录两组患者术前及术后 12 个月的手术时间、术中出血量、住院时间、住院费用、颈痛视觉模拟评分(VAS)、日本骨科协会(JOA)评分、颈椎功能障碍指数(NDI)及脊髓神经功能改善率(IRNF)。术前、术后 1 个月及 2 年,在颈椎侧位 X 线片上记录并比较以下影像学参数:C2 矢状面中轴线至 C7 后上缘的距离(C2-7 SVA)、C2 和 C7 后缘切线的夹角(C2-7 Cobb 角)、T1 上缘与水平线的夹角(T1 斜率)。

结果

两组患者手术时间、术中出血量、住院时间、VAS、JOA 及 NDI 评分比较,差异均无统计学意义(P > 0.05);但 A 组住院费用明显高于 B 组(P < 0.05)。两组患者术后 2 年 VAS 和 NDI 评分均明显降低(P < 0.05),JOA 评分明显升高(P < 0.05)。两组患者 VAS、JOA 和 IRNF 比较,差异均无统计学意义(P > 0.05);但 A 组 NDI 评分优于 B 组(P < 0.05)。影像学参数方面,两组患者术前 C2-7 SVA、C2-7 Cobb 角和 T1 斜率比较,差异均无统计学意义(P > 0.05);术后 C2-7 SVA 和 T1 斜率增加(P < 0.05),C2-7 Cobb 角减小(P < 0.05)。术后 2 年,两组患者 C2-7 Cobb 角和 T1 斜率比较,差异均无统计学意义(P > 0.05);但 A 组 C2-7 SVA 优于 B 组(P < 0.05)。术前与术后 C2-7 SVA 差值与 NDI 评分呈负相关(P < 0.05)。

结论

钛板或锚固定后路单开门椎管扩大成形术治疗 MCSM 均取得了良好的临床疗效。但钛板固定患者颈椎功能状态更好,而锚固定患者住院费用更低。两种方法均可导致颈椎前倾角,但钛板固定后颈椎矢状位平衡更好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/152d/6883605/5449bba65f19/13018_2019_1454_Fig1_HTML.jpg

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