National Jewish Health, Denver (Dr Krefft, Ms Wolff, Ms Zell-Baran, Dr Strand, Dr Gottschall, Dr Meehan, Dr Rose); Veterans Administration Eastern Colorado Health Care System (Dr Krefft); University of Colorado Anschutz Medical Campus (Dr Krefft, Dr Rose); Colorado School of Public Health (Dr Krefft, Ms Zell-Baran, Dr Strand, Dr Rose); University of Colorado (Dr Gottschall, Dr Meehan), Aurora, Colorado.
J Occup Environ Med. 2020 May;62(5):337-343. doi: 10.1097/JOM.0000000000001817.
Persistent respiratory symptoms following post-9/11 military deployment to Iraq and Afghanistan are well-recognized, but the spectrum of respiratory diseases remains poorly characterized. This study describes deployment-related respiratory diseases and the diagnostic utility of resting and exercise pulmonary function testing.
Between 2009 and 2017, 127 consecutive military workers ("deployers") with new-onset respiratory symptoms underwent clinical evaluation. Deployment-related respiratory diseases were classified as proximal and/or distal. Using descriptive statistics and logistic regression, we analyzed lung function parameters associated with deployment-related distal lung disease (DDLD).
Common deployment-related respiratory diseases included asthma (31.5%), intermittent laryngeal obstruction (14.2%), rhinosinusitis (15%), and DDLD (68.5%). Decreased diffusion capacity (odds ratio [OR] = 4.6, 95% confidence interval [CI]: 1.4 to 15.1, P = 0.01) was significantly associated with DDLD.
A comprehensive diagnostic approach may identify a spectrum of proximal and distal respiratory diseases that can occur in symptomatic post-9/11 deployers, requiring a personalized approach to care.
9/11 后军事部署到伊拉克和阿富汗后持续存在的呼吸道症状是众所周知的，但呼吸道疾病的范围仍未得到很好的描述。本研究描述了与部署相关的呼吸道疾病以及静息和运动肺功能测试的诊断效用。
2009 年至 2017 年间，127 名连续出现新发呼吸道症状的现役军人（“部署者”）接受了临床评估。将与部署相关的呼吸道疾病分为近端和/或远端。使用描述性统计和逻辑回归分析，我们分析了与与部署相关的远端肺疾病（DDLD）相关的肺功能参数。
常见的与部署相关的呼吸道疾病包括哮喘（31.5%）、间歇性喉阻塞（14.2%）、鼻-鼻窦炎（15%）和 DDLD（68.5%）。弥散能力下降（比值比[OR] = 4.6，95%置信区间[CI]：1.4 至 15.1，P = 0.01）与 DDLD 显著相关。
综合诊断方法可以识别出一系列可能发生在 9/11 后出现症状的现役军人中的近端和远端呼吸道疾病，需要个性化的护理方法。
