Elgendy Marwa O, Hassan Amira H, Saeed Haitham, Abdelrahim Mohamed E, Eldin Randa Salah
Department of Clinical pharmacy, Teaching Hospital of Faculty of Medicine, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt; Department of Clinical pharmacy, Faculty of Pharmacy, Nahda university, Egypt.
Department of Pharmaceutics, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt.
Pulm Pharmacol Ther. 2020 Apr;61:101900. doi: 10.1016/j.pupt.2020.101900. Epub 2020 Jan 24.
The present work aimed to study the role of metered-dose inhalers (MDI) verbal counseling on asthmatic children patients inhalation technique and their pulmonary functions.
In this study many children younger than 18 years old with asthma were collected from University hospital outpatient clinics throughout two years period Their MDI inhalation technique was checked and the number of MDI inhalation technique mistakes were detected and corrected at the first visit and every month for two more visits (three visits). Their peak expiratory flow (PEF) and forced expiratory volume in 1 s (FEV) as a percentage of the forced vital capacity (FVC) were checked at every visit.
81 asthmatic subjects (54 female) younger than 18 years old were collected with a mean (SD) age 14.4 (1.8) years old. Most of the patients' owned MDI contained salbutamol, however, some patients were using Beclometasone MDI or Beclometasone and salbutamol combination MDI. The mean number of correct steps performed was significantly increased (p < 0.05) as the number of visits increased. "Place the MDI mouthpiece between the teeth and seal with lips" and "To maintain slow inhalation rate until lungs are full" were the least steps correctly performed by the asthmatics children studied. There was a significant increase (p < 0.05) in the pulmonary function test scores at the third visit.
MDI's verbal counseling should be repeated and checked at every opportunity, especially with children, to improve and maintain the recommended MDI inhalation technique. That could be a tool to possibly improve patients' pulmonary functions.
本研究旨在探讨定量吸入器(MDI)口头指导对哮喘儿童患者吸入技术及肺功能的作用。
本研究在两年期间从大学医院门诊收集了许多18岁以下的哮喘儿童。在首次就诊时检查他们的MDI吸入技术,检测并纠正MDI吸入技术错误,之后每一个月再进行两次复诊(共三次就诊)。每次就诊时检查他们的呼气峰值流速(PEF)以及一秒用力呼气容积(FEV)占用力肺活量(FVC)的百分比。
收集了81名18岁以下的哮喘受试者(54名女性),平均(标准差)年龄为14.4(1.8)岁。大多数患者拥有的MDI含有沙丁胺醇,然而,一些患者使用的是倍氯米松MDI或倍氯米松与沙丁胺醇联合MDI。随着就诊次数的增加,正确执行步骤的平均数量显著增加(p<0.05)。“将MDI吸嘴置于牙齿之间并用嘴唇密封”和“保持缓慢吸气速度直至肺部充满”是所研究的哮喘儿童执行最少的步骤。第三次就诊时肺功能测试分数有显著提高(p<0.05)。
应反复并随时检查MDI的口头指导,尤其是对儿童,以改善并维持推荐的MDI吸入技术。这可能是改善患者肺功能的一种手段。