Bel'skaya Lyudmila V, Sarf Elena A, Kosenok Victor K
Biochemistry Research Laboratory, Omsk State Pedagogical University, 14, Tukhachevsky str, Omsk, 644043, Russia.
Chair of Oncology with Radiotherapy, Omsk State Medical Academy, 12, Lenina str, Omsk, 644099, Russia.
J Oral Biol Craniofac Res. 2020 Apr-Jun;10(2):59-65. doi: 10.1016/j.jobcr.2020.02.004. Epub 2020 Feb 14.
Recently, the attention of researchers to the study of the properties of human saliva, as a material with unique properties and diagnostic capabilities, has increased.
to study the connection of the biochemical composition of saliva and blood plasma in the norm, depending on gender and age.
107 volunteers took part in the study, including 46 female (37.2 ± 3.9 years old) and 61 male (36.1 ± 2.8 years old). In all samples of saliva and blood plasma, 16 biochemical parameters were determined, including mineral and protein composition, enzyme activity. Non-parametric statistical methods were used to process the data.
It has been shown that it is difficult to establish an unambiguous relation between biochemical parameters of saliva and blood plasma. The calculation of the Spearman correlation coefficients showed that only 7 of the 16 parameters demonstrate the presence of a weak correlation between the content in saliva and plasma.
In general, the determination of the composition of saliva may have an independent diagnostic value; in this case, drawing a parallel with the composition of serum and blood plasma is not advisable. Nevertheless, the use of saliva in clinical laboratory diagnostics is associated with the need to establish criteria for the norm and pathology for each biochemical parameter.
近年来，作为一种具有独特性质和诊断能力的物质，人体唾液的性质研究受到了研究人员越来越多的关注。
研究正常情况下唾液和血浆的生化组成之间的联系，以及性别和年龄对其的影响。
107名志愿者参与了该研究，其中包括46名女性（37.2±3.9岁）和61名男性（36.1±2.8岁）。在所有唾液和血浆样本中，测定了16种生化参数，包括矿物质和蛋白质组成、酶活性。采用非参数统计方法处理数据。
研究表明，唾液和血浆的生化参数之间难以建立明确的关系。斯皮尔曼相关系数的计算表明，16个参数中只有7个显示出唾液和血浆中含量之间存在弱相关性。
总体而言，唾液成分的测定可能具有独立的诊断价值；在这种情况下，将其与血清和血浆成分进行对比是不可取的。然而，在临床实验室诊断中使用唾液与为每个生化参数建立正常标准和病理标准的必要性相关。
