Butsanets P A, Baik A S, Shugaev A G, Kuznetsov Vl V
Timiryazev Institute of Plant Physiology, Russian Academy of Science, 127276, Moscow, Russia.
Dokl Biochem Biophys. 2019 Nov;489(1):367-369. doi: 10.1134/S1607672919060036. Epub 2020 Mar 4.
The effect of melatonin on respiration and production (release) of hydrogen peroxide during succinate oxidation in mitochondria isolated from lupine cotyledons and epicotyls of pea seedlings was studied. It was shown for the first time that melatonin (10-10 M) had a significant inhibitory effect on the production of peroxide by plant mitochondria, which was characterized by concentration dependence and species specificity. At the same time, melatonin (at a concentration of up to 100 μM) had virtually no effect on mitochondrial respiration rate and respiratory control coefficient. The results confirm the antioxidant function of melatonin and indicate that it is involved in the regulation of ROS levels and maintenance of redox balance in plant mitochondria.
研究了褪黑素对从羽扇豆子叶和豌豆幼苗上胚轴分离的线粒体在琥珀酸氧化过程中呼吸作用及过氧化氢产生（释放）的影响。首次表明，褪黑素（10⁻¹⁰ M）对植物线粒体中过氧化物的产生具有显著抑制作用，其具有浓度依赖性和物种特异性。同时，褪黑素（浓度高达100 μM）对线粒体呼吸速率和呼吸控制系数几乎没有影响。这些结果证实了褪黑素的抗氧化功能，并表明它参与植物线粒体中活性氧水平的调节和氧化还原平衡的维持。
