血液系统恶性肿瘤患者的抑郁、焦虑和压力及其与生活质量的关联：一项横断面研究。
Depression, anxiety and stress among patients with hematological malignancies and the association with quality of life: a cross-sectional study.
作者信息
Papathanasiou Ioanna V, Kelepouris Konstantinos, Valari Chrisoula, Papagiannis Dimitrios, Tzavella Foteini, Kourkouta Lambrini, Tsaras Konstantinos, Fradelos Evangelos C
机构信息
General Department, University of Thessaly, Larissa, Greece.
Emergency Department, General Hospital of Karditsa, Karditsa, Greece.
出版信息
Med Pharm Rep. 2020 Jan;93(1):62-68. doi: 10.15386/mpr-1502. Epub 2020 Jan 31.
AIM
To evaluate psychological distress and quality of life of patients with hematological malignancies, as well as to identify the prognostic factors that aggravate their condition.
METHODS
A cross-sectional, descriptive study including 87 patients with Hematological Malignancies was conducted. Data were collected with an anonymous questionnaire consisted by A) a sheet with socio-demographic characteristics, B) the Depression, Stress and Stress Scale (DASS21), and C) World Health Organization Life Quality Scale (WHOQOL - BREF30). The processing and statistical analysis of the empirical material of the research were done using the SPSS (Statistical Package for Social Science) 22.0.
RESULTS
The results showed that the age of the sample averaged 71.22 years (SD = 8.71). Regarding their marital status, single mothers were 9.2%, married 62.1%. With regard to disease-related features, 28.7% of patients had Hodgkin's Lymphoma, 27.6% Chronic Lymphocytic Leukemia, 27.6% MDL and 16.1% of patients had myelodysplastic syndrome Multiple myeloma. In the investigation of the relationship between the Mental health Scale and the Quality of Life, negative correlations of Depression, Stress, Stress and the total DAS Scale with all dimensions of Patient Quality of Life were found.
CONCLUSIONS
Higher levels of psychological distress and poor mental health are associated with a low level of quality of life.
目的
评估血液系统恶性肿瘤患者的心理困扰和生活质量，并确定加重其病情的预后因素。
方法
开展一项横断面描述性研究，纳入87例血液系统恶性肿瘤患者。通过一份匿名问卷收集数据，问卷包括：A）一份包含社会人口学特征的表格；B）抑郁、焦虑和压力量表（DASS21）；C）世界卫生组织生活质量量表（WHOQOL - BREF30）。研究实证材料的处理和统计分析使用SPSS（社会科学统计软件包）22.0完成。
结果
结果显示，样本年龄平均为71.22岁（标准差 = 8.71）。关于婚姻状况，单身母亲占9.2%，已婚占62.1%。关于疾病相关特征，28.7%的患者患有霍奇金淋巴瘤，27.6%患有慢性淋巴细胞白血病，27.6%患有骨髓增生异常综合征，16.1%的患者患有骨髓增生异常综合征/多发性骨髓瘤。在心理健康量表与生活质量关系的调查中，发现抑郁、焦虑、压力及DAS量表总分与患者生活质量的所有维度均呈负相关。
结论
较高水平的心理困扰和较差的心理健康与较低的生活质量相关。
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