• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

人类免疫缺陷病毒的复制：单生长周期条件下感染性病毒的产量

Replication of human immunodeficiency virus: yield of infectious virus under single growth cycle conditions.

作者信息

Dianzani F, Antonelli G, Capobianchi M R, De Marco F

机构信息

Institute of Virology, University of Rome, Italy.

出版信息

Arch Virol. 1988;103(1-2):127-31. doi: 10.1007/BF01319814.

DOI:10.1007/BF01319814
PMID:3214269
Abstract

Replication kinetics of HIV was studied under single growth cycle conditions by backtitrating infectious virus released or remained cell-associated at each time point. Under these conditions HIV seems to replicate faster than previously estimated. The amount of cell-associated virus always exceeds the one detectable in the medium.

摘要

在单个生长周期条件下，通过对每个时间点释放的或仍与细胞相关的感染性病毒进行反向滴定，研究了HIV的复制动力学。在这些条件下，HIV的复制似乎比先前估计的要快。与细胞相关的病毒量总是超过培养基中可检测到的量。

相似文献

1
Replication of human immunodeficiency virus: yield of infectious virus under single growth cycle conditions.人类免疫缺陷病毒的复制：单生长周期条件下感染性病毒的产量
Arch Virol. 1988;103(1-2):127-31. doi: 10.1007/BF01319814.
2
LuSIV cells: a reporter cell line for the detection and quantitation of a single cycle of HIV and SIV replication.LuSIV细胞：一种用于检测和定量HIV和SIV单周期复制的报告细胞系。
Virology. 2000 Aug 1;273(2):307-15. doi: 10.1006/viro.2000.0431.
3
Susceptibility of human immunodeficiency virus to antiviral agents measured by infectious virus yield reduction.通过感染性病毒产量降低来测定人类免疫缺陷病毒对抗病毒药物的敏感性。
Antiviral Res. 1989 Jun-Jul;11(5-6):299-305. doi: 10.1016/0166-3542(89)90039-9.
4
MT-4 plaque formation can distinguish cytopathic subtypes of the human immunodeficiency virus (HIV).MT-4 噬斑形成可区分人类免疫缺陷病毒（HIV）的细胞病变亚型。
Virology. 1988 Nov;167(1):299-301. doi: 10.1016/0042-6822(88)90084-0.
5
Prostaglandin A inhibits replication of human immunodeficiency virus during acute infection.前列腺素A在急性感染期间抑制人类免疫缺陷病毒的复制。
J Gen Virol. 1991 Nov;72 ( Pt 11):2797-800. doi: 10.1099/0022-1317-72-11-2797.
6
Preliminary in vitro growth cycle and transmission studies of HIV-1 in an autologous primary cell assay of blood-derived macrophages and peripheral blood mononuclear cells.在一项由血液来源的巨噬细胞和外周血单核细胞组成的自体原代细胞检测中，对HIV-1进行的初步体外生长周期及传播研究。
Virology. 1996 Dec 15;226(2):205-16. doi: 10.1006/viro.1996.0648.
7
Evaluation of the antiviral effect of new compounds by using cellular cultures.采用细胞培养评估新化合物的抗病毒效果。
Cytotechnology. 1991 Feb;5(Suppl 1):3-6. doi: 10.1007/BF00736794.
8
Cells surviving infection by human immunodeficiency virus type 1: vif or vpu mutants produce non-infectious or markedly less cytopathic viruses.1型人类免疫缺陷病毒感染后存活的细胞：vif或vpu突变体产生无感染性或细胞病变性明显较弱的病毒。
J Gen Virol. 1992 Jan;73 ( Pt 1):77-87. doi: 10.1099/0022-1317-73-1-77.
9
[Inhibition of human immunodeficiency virus replication by azidothymidine (Azitidín Lachema) in cultured cells].
Bratisl Lek Listy. 1993 Feb;94(2):76-80.
10
Concurrent human immunodeficiency virus and mycobacterial infection of macrophages in vitro does not reveal any reciprocal effect.体外人免疫缺陷病毒与巨噬细胞分枝杆菌的并发感染未显示出任何相互作用。
J Infect Dis. 1992 Jan;165(1):80-6. doi: 10.1093/infdis/165.1.80.

引用本文的文献

1
Evaluation of the antiviral effect of new compounds by using cellular cultures.采用细胞培养评估新化合物的抗病毒效果。
Cytotechnology. 1991 Feb;5(Suppl 1):3-6. doi: 10.1007/BF00736794.
2
Unique morphological alterations of the HTLV-I transformed C8166 cells by infection with HIV-1.人嗜T淋巴细胞病毒I型（HTLV-I）转化的C8166细胞经人免疫缺陷病毒1型（HIV-1）感染后的独特形态学改变。
Pathol Oncol Res. 2000;6(1):27-37. doi: 10.1007/BF03032655.
3
Mutual interactions between HIV-1 and cytokines in adherent cells during acute infection.急性感染期间HIV-1与贴壁细胞中细胞因子之间的相互作用。

本文引用的文献

1
Trans-acting transcriptional activation of the long terminal repeat of human T lymphotropic viruses in infected cells.人嗜T淋巴细胞病毒长末端重复序列在受感染细胞中的反式作用转录激活
Science. 1984 Jul 27;225(4660):381-5. doi: 10.1126/science.6330891.
2
Detection, isolation, and continuous production of cytopathic retroviruses (HTLV-III) from patients with AIDS and pre-AIDS.从艾滋病患者和艾滋病前期患者中检测、分离并持续生产细胞病变逆转录病毒（HTLV-III）。
Science. 1984 May 4;224(4648):497-500. doi: 10.1126/science.6200935.
3
pH-independent HIV entry into CD4-positive T cells via virus envelope fusion to the plasma membrane.
Arch Virol. 1994;134(1-2):157-68. doi: 10.1007/BF01379114.
4
CD4-positive lymphoid cells rescue HIV-1 replication from abortively infected human primary endothelial cells.CD4 阳性淋巴细胞可挽救 HIV-1 从感染受阻的人原代内皮细胞中的复制。
Arch Virol. 1993;132(3-4):267-80. doi: 10.1007/BF01309538.
5
Increased human immunodeficiency virus (HIV) expression in chronically infected U937 cells upon in vitro differentiation by hydroxyvitamin D3: roles of interferon and tumor necrosis factor in regulation of HIV production.羟基维生素D3体外诱导慢性感染的U937细胞分化后人类免疫缺陷病毒（HIV）表达增加：干扰素和肿瘤坏死因子在HIV产生调控中的作用
J Virol. 1990 Dec;64(12):5874-82. doi: 10.1128/JVI.64.12.5874-5882.1990.
6
Cytotoxic activity of intestinal lamina propria lymphocytes on human immunodeficiency virus (HIV)-infected cells.肠道固有层淋巴细胞对人类免疫缺陷病毒（HIV）感染细胞的细胞毒性活性。
Immunology. 1992 May;76(1):117-21.
pH 非依赖性的 HIV 通过病毒包膜与质膜融合进入 CD4 阳性 T 细胞。
Cell. 1987 Jun 5;49(5):659-68. doi: 10.1016/0092-8674(87)90542-3.
4
Human immunodeficiency virus infection of monocytic and T-lymphocytic cells: receptor modulation and differentiation induced by phorbol ester.人免疫缺陷病毒对单核细胞和T淋巴细胞的感染：佛波酯诱导的受体调节和分化
Virology. 1987 May;158(1):44-51. doi: 10.1016/0042-6822(87)90236-4.
5
The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain.T4基因编码艾滋病病毒受体，并在免疫系统和大脑中表达。
Cell. 1986 Nov 7;47(3):333-48. doi: 10.1016/0092-8674(86)90590-8.
6
Establishment of a high production system for AIDS retroviruses with a human T-leukemic cell line Molt-4.利用人T白血病细胞系Molt-4建立艾滋病逆转录病毒高产系统。
Cancer Lett. 1986 Mar;30(3):299-310. doi: 10.1016/0304-3835(86)90054-6.
7
Quantitative assays for evaluation of HTLV-III inactivation procedures: tri(N-butyl)phosphate:sodium cholate and beta-propiolactone.用于评估HTLV-III灭活程序的定量测定：磷酸三（正丁基）酯：胆酸钠和β-丙内酯。
Cancer Res. 1985 Sep;45(9 Suppl):4592s-4594s.
8
Studies on the budding process of a temperature-sensitive mutant of murine leukemia virus with a scanning electron microscope.用扫描电子显微镜对鼠白血病病毒温度敏感突变体出芽过程的研究。
J Virol. 1975 Aug;16(2):434-42. doi: 10.1128/JVI.16.2.434-442.1975.