Translational Medicine Programs, Institute of Medicine, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.
School of Surgery, Institute of Medicine, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.
Biomed Res Int. 2020 Feb 18;2020:7243029. doi: 10.1155/2020/7243029. eCollection 2020.
The clinical outcomes of gastric diseases such as chronic gastritis, peptic ulcer, and gastric cancer have been attributed to the interplay of virulence factors of (), host genetic susceptibility, and host immune responses. This study investigated the presence of , , 2, 2, and genes and their association with clinical outcomes.
Chronic gastritis, atrophic gastritis, and intestinal metaplasia specimens were obtained from patients who underwent endoscopy and surgical resection between January 2017 and December 2018; specimens from gastric cancer patients treated between January 2014 and December 2018 were also added. ), host genetic susceptibility, and host immune responses. This study investigated the presence of , , 2, 2, and genes and their association with clinical outcomes. ), host genetic susceptibility, and host immune responses. This study investigated the presence of.
), host genetic susceptibility, and host immune responses. This study investigated the presence of , 2, and genes and their association with clinical outcomes. , 2, and genes and their association with clinical outcomes. =0.033, OR = 2.64; 95% CI = 1.44-4.82, =0.033, OR = 2.64; 95% CI = 1.44-4.82, =0.033, OR = 2.64; 95% CI = 1.44-4.82, /2, and genes and their association with clinical outcomes. =0.033, OR = 2.64; 95% CI = 1.44-4.82.
In this present study, we reported on the virulence genes of infection to reveal their association with increased risk of chronic gastritis, precancerous gastric lesions, and gastric cancer. Precancerous gastric lesions with +/2+/+ genotype increased the risk of gastric cancer.), host genetic susceptibility, and host immune responses. This study investigated the presence of /2, and genes and their association with clinical outcomes.
慢性胃炎、消化性溃疡和胃癌等胃部疾病的临床结果归因于毒力因子（）、宿主遗传易感性和宿主免疫反应的相互作用。本研究调查了存在的、、2、2 和基因及其与临床结果的关联。
本研究收集了 2017 年 1 月至 2018 年 12 月间行内镜和外科切除术的患者的慢性胃炎、萎缩性胃炎和肠上皮化生标本，并添加了 2014 年 1 月至 2018 年 12 月间治疗的胃癌患者的标本。）、宿主遗传易感性和宿主免疫反应。本研究调查了存在的、、2、2 和基因及其与临床结果的关联。）、宿主遗传易感性和宿主免疫反应。本研究调查了存在的。
）、宿主遗传易感性和宿主免疫反应。本研究调查了存在的、2 和基因及其与临床结果的关联。=0.033，OR=2.64；95%CI=1.44-4.82，=0.033，OR=2.64；95%CI=1.44-4.82，=0.033，OR=2.64；95%CI=1.44-4.82，/2，和基因及其与临床结果的关联。=0.033，OR=2.64；95%CI=1.44-4.82。
在本研究中，我们报告了感染的毒力基因，以揭示它们与慢性胃炎、癌前胃病变和胃癌风险增加的关系。具有+/2+/+基因型的癌前胃病变增加了胃癌的风险。）、宿主遗传易感性和宿主免疫反应。本研究调查了存在的、2 和基因及其与临床结果的关联。
