Syed Asad, Benit Natarajan, Alyousef Abdullah A, Alqasim Abdulaziz, Arshad Mohammed
Department of Botany and Microbiology, College of Science, King Saud University, P.O. Box 2455 Riyadh 11451, Saudi Arabia.
Department of Botany, Holy Cross College, Manonmaniam Sundaranar University, Abishekapatti, Tirunelveli 627 012, Tamil Nadu, India.
Saudi J Biol Sci. 2020 Feb;27(2):757-761. doi: 10.1016/j.sjbs.2019.12.031. Epub 2019 Dec 26.
The present study explored the phytochemicals, antibacterial, antioxidant and cytotoxic effect of leaves. The leaves were dried and extracted with various organic solvents. The leaves contained the phytochemicals such as alkaloids, carbohydrates, polyphenols and tannins respectively. Antimicrobial potentials of the extracts were determined by performing the disc diffusion techniques. Results revealed that different organic solvents extracts namely methanol, ethanol and ethyl acetate extracts documented comparatively good activity against the studied microbial strains. The methanol extract of leaves of showed combatively better antioxidant potential. The tested plant leaf extract showed high activity against human lung cancer cells than breast cancer cell lines. 250 µg/ml plants extract showed 84 ± 2.8% toxicity against human lung cancer cells.
本研究探讨了树叶的植物化学成分、抗菌、抗氧化和细胞毒性作用。将树叶干燥并用各种有机溶剂提取。树叶分别含有生物碱、碳水化合物、多酚和单宁等植物化学成分。通过纸片扩散法测定提取物的抗菌潜力。结果显示，不同的有机溶剂提取物，即甲醇、乙醇和乙酸乙酯提取物，对所研究的微生物菌株表现出相对较好的活性。树叶的甲醇提取物表现出相对较好的抗氧化潜力。经测试，该植物叶提取物对人肺癌细胞的活性高于乳腺癌细胞系。250µg/ml的植物提取物对人肺癌细胞显示出84±2.8%的毒性。
