Ratan Zubair Ahmed, Haidere Mohammad Faisal, Nurunnabi Md, Shahriar Sadi Md, Ahammad A J Saleh, Shim Youn Young, Reaney Martin J T, Cho Jae Youl
Department of Integrative Biotechnology, Biomedical Institute for Convergence at SKKU (BICS), Sungkyunkwan University, Suwon 16419, Korea.
Department of Biomedical Engineering, Khulna University of Engineering and Technology, Khulna 9203, Bangladesh.
Cancers (Basel). 2020 Apr 1;12(4):855. doi: 10.3390/cancers12040855.
Nanobiotechnology has grown rapidly and become an integral part of modern disease diagnosis and treatment. Biosynthesized silver nanoparticles (AgNPs) are a class of eco-friendly, cost-effective and biocompatible agents that have attracted attention for their possible biomedical and bioengineering applications. Like many other inorganic and organic nanoparticles, such as AuNPs, iron oxide and quantum dots, AgNPs have also been widely studied as components of advanced anticancer agents in order to better manage cancer in the clinic. AgNPs are typically produced by the action of reducing reagents on silver ions. In addition to numerous laboratory-based methods for reduction of silver ions, living organisms and natural products can be effective and superior source for synthesis of AgNPs precursors. Currently, plants, bacteria and fungi can afford biogenic AgNPs precursors with diverse geometries and surface properties. In this review, we summarized the recent progress and achievements in biogenic AgNPs synthesis and their potential uses as anticancer agents.
纳米生物技术发展迅速，已成为现代疾病诊断和治疗不可或缺的一部分。生物合成的银纳米颗粒（AgNPs）是一类生态友好、成本效益高且具有生物相容性的试剂，因其可能的生物医学和生物工程应用而备受关注。与许多其他无机和有机纳米颗粒一样，如金纳米颗粒、氧化铁和量子点，AgNPs也作为先进抗癌剂的成分被广泛研究，以便在临床上更好地治疗癌症。AgNPs通常通过还原剂对银离子的作用产生。除了众多基于实验室的银离子还原方法外，生物体和天然产物可以是合成AgNPs前体的有效且优质的来源。目前，植物、细菌和真菌能够提供具有不同几何形状和表面性质的生物源AgNPs前体。在本综述中，我们总结了生物源AgNPs合成的最新进展和成果及其作为抗癌剂的潜在用途。
