Xu Rong, Liu Xiaochen, Peng Bing, Liu Peibin, Li Zhuang, Dai Yueting, Xiao Shijun
Internationally Cooperative Research Center of China for New Germplasm Breeding of Edible Mushroom, Jilin Agricultural University, Changchun 130118, China.
College of Plant Protection, Jilin Agricultural University, Changchun 130118, China.
Pathogens. 2020 Mar 20;9(3):232. doi: 10.3390/pathogens9030232.
, which causes cobweb disease in edible mushrooms, is one of the major fungal pathogens. Our previous studies focused on the genetic and morphological characterization of this fungus, as well as its pathogenicity and the identification of appropriate fungicides. However, little is known about the genome characters, pathogenic genes, and molecular pathogenic mechanisms of . Herein, we reported a high-quality de novo genomic sequence of and compared it with closely-related fungi. The assembled genome was 36.69 Mb, consisting of eight contigs, with an N50 of 4.76 Mb. This genome was similar in size to that of , and shared highly conserved syntenic blocks and a few inversions with . Phylogenetic analysis revealed that, within the Hypocreaceae, was closer to than to , which is consistent with phenotypic evidence. A significant number of the predicted expanded gene families were strongly associated with pathogenicity, virulence, and adaptation. Our findings will be instrumental for the understanding of fungi-fungi interactions, and for exploring efficient management strategies to control cobweb disease.
导致食用菌蛛网病的[病原菌名称]是主要的真菌病原体之一。我们之前的研究集中在这种真菌的遗传和形态特征、致病性以及合适杀菌剂的鉴定上。然而，关于[病原菌名称]的基因组特征、致病基因和分子致病机制知之甚少。在此，我们报道了[病原菌名称]的高质量从头基因组序列，并将其与密切相关的真菌进行了比较。组装后的[病原菌名称]基因组为36.69 Mb，由8个重叠群组成，N50为4.76 Mb。该基因组大小与[比较对象名称1]相似，与[比较对象名称2]共享高度保守的共线性区域和一些倒位。系统发育分析表明，在肉座菌科内，[病原菌名称]与[比较对象名称1]的亲缘关系比与[比较对象名称2]更近，这与表型证据一致。大量预测的扩增基因家族与致病性、毒力和适应性密切相关。我们的研究结果将有助于理解真菌 - 真菌相互作用，并探索控制蛛网病的有效管理策略。
