使用聚集诱导发光硫代邻苯二甲腈染料的多价纳米颗粒进行细菌凝集。
Agglutination of bacteria using polyvalent nanoparticles of aggregation-induced emissive thiophthalonitrile dyes.
作者信息
Schmidt Bettina, Sankaran Shrikrishnan, Stegemann Linda, Strassert Cristian A, Jonkheijm Pascal, Voskuhl Jens
机构信息
Bioinspired Molecular Engineering Laboratory of the MIRA Institute for Biomedical Technology and Technical Medicine, University of Twente, P.O. Box 217, 7500 AE Enschede, Netherlands.
出版信息
J Mater Chem B. 2016 Jul 21;4(27):4732-4738. doi: 10.1039/c6tb01210h. Epub 2016 Jun 24.
A novel class of aggregation-induced emissive bis(phenylthio)phthalonitrile dyes were synthesized. These dyes assembled into nanoparticles that were equipped with mannose units. The nanoparticles underwent selective interactions with lectins and bacteria. The bright fluorescent aggregates aid in the visualization of the agglutination of bacteria.
合成了一类新型的聚集诱导发光双（苯硫基）邻苯二甲腈染料。这些染料组装成带有甘露糖单元的纳米颗粒。纳米颗粒与凝集素和细菌发生选择性相互作用。明亮的荧光聚集体有助于观察细菌的凝集。
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